Konings M - Search Results

1

A Falciformispora senegalensis grain model in Galleria mellonella larvae.

Ma J, Konings M, Verbon A, van de Sande WWJ. Ma J, et al. Among authors: konings m. Med Mycol. 2023 Aug 2;61(8):myad070. doi: 10.1093/mmy/myad070. Med Mycol. 2023. PMID: 37451815 Free PMC article.

2

Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma.

Lim W, Melse Y, Konings M, Phat Duong H, Eadie K, Laleu B, Perry B, Todd MH, Ioset JR, van de Sande WWJ. Lim W, et al. Among authors: konings m. PLoS Negl Trop Dis. 2018 Apr 26;12(4):e0006437. doi: 10.1371/journal.pntd.0006437. eCollection 2018 Apr. PLoS Negl Trop Dis. 2018. PMID: 29698504 Free PMC article.

3

Madurella mycetomatis, the main causative agent of eumycetoma, is highly susceptible to olorofim.

Lim W, Eadie K, Konings M, Rijnders B, Fahal AH, Oliver JD, Birch M, Verbon A, van de Sande W. Lim W, et al. Among authors: konings m. J Antimicrob Chemother. 2020 Apr 1;75(4):936-941. doi: 10.1093/jac/dkz529. J Antimicrob Chemother. 2020. PMID: 31904836 Free PMC article.

4

Proteomic analysis of the processes leading to Madurella mycetomatis grain formation in Galleria mellonella larvae.

Sheehan G, Konings M, Lim W, Fahal A, Kavanagh K, van de Sande WWJ. Sheehan G, et al. Among authors: konings m. PLoS Negl Trop Dis. 2020 Apr 8;14(4):e0008190. doi: 10.1371/journal.pntd.0008190. eCollection 2020 Apr. PLoS Negl Trop Dis. 2020. PMID: 32267851 Free PMC article.

5

The synthetic synergistic cinnamon oil CIN-102 is active against Madurella mycetomatis, the most common causative agent of mycetoma.

Konings M, Eadie K, Lim W, Fahal AH, Mouton J, Tesse N, van de Sande WWJ. Konings M, et al. PLoS Negl Trop Dis. 2021 Jun 9;15(6):e0009488. doi: 10.1371/journal.pntd.0009488. eCollection 2021 Jun. PLoS Negl Trop Dis. 2021. PMID: 34106933 Free PMC article.

6

Inhibiting DHN- and DOPA-melanin biosynthesis pathway increased the therapeutic value of itraconazole in Madurella mycetomatis infected Galleria mellonella.

Lim W, Konings M, Parel F, Eadie K, Strepis N, Fahal A, Verbon A, van de Sande WWJ. Lim W, et al. Among authors: konings m. Med Mycol. 2022 Feb 2;60(2):myac003. doi: 10.1093/mmy/myac003. Med Mycol. 2022. PMID: 35064672 Free PMC article.

7

Screening the pandemic response box identified benzimidazole carbamates, Olorofim and ravuconazole as promising drug candidates for the treatment of eumycetoma.

Lim W, Nyuykonge B, Eadie K, Konings M, Smeets J, Fahal A, Bonifaz A, Todd M, Perry B, Samby K, Burrows J, Verbon A, van de Sande W. Lim W, et al. Among authors: konings m. PLoS Negl Trop Dis. 2022 Feb 4;16(2):e0010159. doi: 10.1371/journal.pntd.0010159. eCollection 2022 Feb. PLoS Negl Trop Dis. 2022. PMID: 35120131 Free PMC article.

8

Madurella mycetomatis grains within a eumycetoma lesion are clonal.

Nyuykonge B, Siddig EE, Konings M, Bakhiet S, Verbon A, Klaassen CHW, Fahal AH, van de Sande WWJ. Nyuykonge B, et al. Among authors: konings m. Med Mycol. 2022 Jul 29;60(7):myac051. doi: 10.1093/mmy/myac051. Med Mycol. 2022. PMID: 35833294 Free PMC article.

9

The combination of manogepix and itraconazole is synergistic and inhibits the growth of Madurella mycetomatis in vitro but not in vivo.

Konings M, Eadie K, Strepis N, Nyuykonge B, Fahal AH, Verbon A, van de Sande WWJ. Konings M, et al. Med Mycol. 2023 Nov 6;61(11):myad118. doi: 10.1093/mmy/myad118. Med Mycol. 2023. PMID: 37960934 Free PMC article.

10

Complete Genome Sequence of the Itraconazole Decreased Susceptible Madurella fahalii Type-Strain CBS 129176.

Konings M, Gerrits van den Ende B, Raats MWJ, Fahal AH, van de Sande WWJ, Hagen F. Konings M, et al. Mycopathologia. 2024 Jan 17;189(1):6. doi: 10.1007/s11046-023-00807-0. Mycopathologia. 2024. PMID: 38231295 Free PMC article.

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