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Programming tissue-sensing T cells that deliver therapies to the brain.
Simic MS, Watchmaker PB, Gupta S, Wang Y, Sagan SA, Duecker J, Shepherd C, Diebold D, Pineo-Cavanaugh P, Haegelin J, Zhu R, Ng B, Yu W, Tonai Y, Cardarelli L, Reddy NR, Sidhu SS, Troyanskaya O, Hauser SL, Wilson MR, Zamvil SS, Okada H, Lim WA. Simic MS, et al. Among authors: hauser sl. Science. 2024 Dec 6;386(6726):eadl4237. doi: 10.1126/science.adl4237. Epub 2024 Dec 6. Science. 2024. PMID: 39636984
Long-term analysis of infections and associated risk factors in patients with multiple sclerosis treated with ocrelizumab: pooled analysis of 13 interventional clinical trials.
Derfuss T, Bermel R, Lin CJ, Hauser SL, Kappos L, Vollmer T, Comi G, Giovannoni G, Hartung HP, Weber MS, Wang J, Jessop N, Chognot C, Craveiro L, Bar-Or A. Derfuss T, et al. Among authors: hauser sl. Ther Adv Neurol Disord. 2024 Oct 8;17:17562864241277736. doi: 10.1177/17562864241277736. eCollection 2024. Ther Adv Neurol Disord. 2024. PMID: 39399100 Free PMC article.
Antigen specificity of clonally-enriched CD8+ T cells in multiple sclerosis.
Mittl K, Hayashi F, Dandekar R, Schubert RD, Gerdts J, Oshiro L, Loudermilk R, Greenfield A, Augusto DG, Ramesh A, Tran E, Koshal K, Kizer K, Dreux J, Cagalingan A, Schustek F, Flood L, Moore T, Kirkemo LL, Cooper T, Harms M, Gomez R; University of California, San Francisco MS-EPIC Team; Sibener L, Cree BAC, Hauser SL, Hollenbach JA, Gee M, Wilson MR, Zamvil SS, Sabatino JJ. Mittl K, et al. Among authors: hauser sl. bioRxiv [Preprint]. 2024 Oct 17:2024.09.07.611010. doi: 10.1101/2024.09.07.611010. bioRxiv. 2024. PMID: 39282370 Free PMC article. Preprint.
Transcobalamin receptor antibodies in autoimmune vitamin B12 central deficiency.
Pluvinage JV, Ngo T, Fouassier C, McDonagh M, Holmes BB, Bartley CM, Kondapavulur S, Hurabielle C, Bodansky A, Pai V, Hinman S, Aslanpour A, Alvarenga BD, Zorn KC, Zamecnik C, McCann A, Asencor AI, Huynh T, Browne W, Tubati A, Haney MS, Douglas VC, Louine M, Cree BAC, Hauser SL, Seeley W, Baranzini SE, Wells JA, Spudich S, Farhadian S, Ramachandran PS, Gillum L, Hales CM, Zikherman J, Anderson MS, Yazdany J, Smith B, Nath A, Suh G, Flanagan EP, Green AJ, Green R, Gelfand JM, DeRisi JL, Pleasure SJ, Wilson MR. Pluvinage JV, et al. Among authors: hauser sl. Sci Transl Med. 2024 Jun 26;16(753):eadl3758. doi: 10.1126/scitranslmed.adl3758. Epub 2024 Jun 26. Sci Transl Med. 2024. PMID: 38924428 Free PMC article.
Inflammatory and neurodegenerative serum protein biomarkers increase sensitivity to detect clinical and radiographic disease activity in multiple sclerosis.
Chitnis T, Qureshi F, Gehman VM, Becich M, Bove R, Cree BAC, Gomez R, Hauser SL, Henry RG, Katrib A, Lokhande H, Paul A, Caillier SJ, Santaniello A, Sattarnezhad N, Saxena S, Weiner H, Yano H, Baranzini SE. Chitnis T, et al. Among authors: hauser sl. Nat Commun. 2024 May 20;15(1):4297. doi: 10.1038/s41467-024-48602-9. Nat Commun. 2024. PMID: 38769309 Free PMC article.
Genetic mapping across autoimmune diseases reveals shared associations and mechanisms.
Lincoln MR, Connally N, Axisa PP, Gasperi C, Mitrovic M, van Heel D, Wijmenga C, Withoff S, Jonkers IH, Padyukov L; International Multiple Sclerosis Genetics Consortium; Rich SS, Graham RR, Gaffney PM, Langefeld CD, Vyse TJ, Hafler DA, Chun S, Sunyaev SR, Cotsapas C. Lincoln MR, et al. Nat Genet. 2024 May;56(5):838-845. doi: 10.1038/s41588-024-01732-8. Epub 2024 May 13. Nat Genet. 2024. PMID: 38741015
An autoantibody signature predictive for multiple sclerosis.
Zamecnik CR, Sowa GM, Abdelhak A, Dandekar R, Bair RD, Wade KJ, Bartley CM, Kizer K, Augusto DG, Tubati A, Gomez R, Fouassier C, Gerungan C, Caspar CM, Alexander J, Wapniarski AE, Loudermilk RP, Eggers EL, Zorn KC, Ananth K, Jabassini N, Mann SA, Ragan NR, Santaniello A, Henry RG, Baranzini SE, Zamvil SS, Sabatino JJ Jr, Bove RM, Guo CY, Gelfand JM, Cuneo R, von Büdingen HC, Oksenberg JR, Cree BAC, Hollenbach JA, Green AJ, Hauser SL, Wallin MT, DeRisi JL, Wilson MR. Zamecnik CR, et al. Among authors: hauser sl. Nat Med. 2024 May;30(5):1300-1308. doi: 10.1038/s41591-024-02938-3. Epub 2024 Apr 19. Nat Med. 2024. PMID: 38641750
Implicit neural representations in light microscopy.
Hauser SL, Brosig J, Murthy B, Attardo A, Kist AM. Hauser SL, et al. Biomed Opt Express. 2024 Mar 6;15(4):2175-2186. doi: 10.1364/BOE.515517. eCollection 2024 Apr 1. Biomed Opt Express. 2024. PMID: 38633078 Free PMC article.
Synaptic injury in the inner plexiform layer of the retina is associated with progression in multiple sclerosis.
Cordano C, Werneburg S, Abdelhak A, Bennett DJ, Beaudry-Richard A, Duncan GJ, Oertel FC, Boscardin WJ, Yiu HH, Jabassini N, Merritt L, Nocera S, Sin JH, Samana IP, Condor Montes SY, Ananth K, Bischof A; UCSF MS EPIC Team; Nourbakhsh B, Hauser SL, Cree BAC, Emery B, Schafer DP, Chan JR, Green AJ. Cordano C, et al. Among authors: hauser sl. Cell Rep Med. 2024 Apr 16;5(4):101490. doi: 10.1016/j.xcrm.2024.101490. Epub 2024 Apr 3. Cell Rep Med. 2024. PMID: 38574736 Free PMC article.
467 results