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SIX1 and EWS/FLI1 co-regulate an anti-metastatic gene network in Ewing Sarcoma.
Hughes CJ, Fields KM, Danis EP, Hsu JY, Neelakantan D, Vincent MY, Gustafson AL, Oliphant MJ, Sreekanth V, Zaberezhnyy V, Costello JC, Jedlicka P, Ford HL. Hughes CJ, et al. Among authors: costello jc. Nat Commun. 2023 Jul 19;14(1):4357. doi: 10.1038/s41467-023-39945-w. Nat Commun. 2023. PMID: 37468459 Free PMC article.
Identification of a Small-Molecule Inhibitor That Disrupts the SIX1/EYA2 Complex, EMT, and Metastasis.
Zhou H, Blevins MA, Hsu JY, Kong D, Galbraith MD, Goodspeed A, Culp-Hill R, Oliphant MUJ, Ramirez D, Zhang L, Trinidad-Pineiro J, Mathews Griner L, King R, Barnaeva E, Hu X, Southall NT, Ferrer M, Gustafson DL, Regan DP, D'Alessandro A, Costello JC, Patnaik S, Marugan J, Zhao R, Ford HL. Zhou H, et al. Among authors: costello jc. Cancer Res. 2020 Jun 15;80(12):2689-2702. doi: 10.1158/0008-5472.CAN-20-0435. Epub 2020 Apr 27. Cancer Res. 2020. PMID: 32341035 Free PMC article.
KDM5A and PHF2 positively control expression of pro-metastatic genes repressed by EWS/Fli1, and promote growth and metastatic properties in Ewing sarcoma.
McCann TS, Parrish JK, Hsieh J, Sechler M, Sobral LM, Self C, Jones KL, Goodspeed A, Costello JC, Jedlicka P. McCann TS, et al. Among authors: costello jc. Oncotarget. 2020 Oct 27;11(43):3818-3831. doi: 10.18632/oncotarget.27737. eCollection 2020 Oct 27. Oncotarget. 2020. PMID: 33196691 Free PMC article.
MAP3K7 Loss Drives Enhanced Androgen Signaling and Independently Confers Risk of Recurrence in Prostate Cancer with Joint Loss of CHD1.
Jillson LK, Rider LC, Rodrigues LU, Romero L, Karimpour-Fard A, Nieto C, Gillette C, Torkko K, Danis E, Smith EE, Nolley R, Peehl DM, Lucia MS, Costello JC, Cramer SD. Jillson LK, et al. Among authors: costello jc. Mol Cancer Res. 2021 Jul;19(7):1123-1136. doi: 10.1158/1541-7786.MCR-20-0913. Epub 2021 Apr 12. Mol Cancer Res. 2021. PMID: 33846123 Free PMC article.
IL13Rα2 Promotes Proliferation and Outgrowth of Breast Cancer Brain Metastases.
Márquez-Ortiz RA, Contreras-Zárate MJ, Tesic V, Alvarez-Eraso KLF, Kwak G, Littrell Z, Costello JC, Sreekanth V, Ormond DR, Karam SD, Kabos P, Cittelly DM. Márquez-Ortiz RA, et al. Among authors: costello jc. Clin Cancer Res. 2021 Nov 15;27(22):6209-6221. doi: 10.1158/1078-0432.CCR-21-0361. Epub 2021 Sep 20. Clin Cancer Res. 2021. PMID: 34544797 Free PMC article.
92 results