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LONRF2 is a protein quality control ubiquitin ligase whose deficiency causes late-onset neurological deficits.
Li D, Johmura Y, Morimoto S, Doi M, Nakanishi K, Ozawa M, Tsunekawa Y, Inoue-Yamauchi A, Naruse H, Matsukawa T, Takeshita Y, Suzuki N, Aoki M, Nishiyama A, Zeng X, Konishi C, Suzuki N, Nishiyama A, Harris AS, Morita M, Yamaguchi K, Furukawa Y, Nakai K, Tsuji S, Yamazaki S, Yamanashi Y, Shimada S, Okada T, Okano H, Toda T, Nakanishi M. Li D, et al. Among authors: okano h. Nat Aging. 2023 Aug;3(8):1001-1019. doi: 10.1038/s43587-023-00464-4. Epub 2023 Jul 20. Nat Aging. 2023. PMID: 37474791
Disease progression of human SOD1 (G93A) transgenic ALS model rats.
Matsumoto A, Okada Y, Nakamichi M, Nakamura M, Toyama Y, Sobue G, Nagai M, Aoki M, Itoyama Y, Okano H. Matsumoto A, et al. Among authors: okano h. J Neurosci Res. 2006 Jan;83(1):119-33. doi: 10.1002/jnr.20708. J Neurosci Res. 2006. PMID: 16342121
Establishment of In Vitro FUS-Associated Familial Amyotrophic Lateral Sclerosis Model Using Human Induced Pluripotent Stem Cells.
Ichiyanagi N, Fujimori K, Yano M, Ishihara-Fujisaki C, Sone T, Akiyama T, Okada Y, Akamatsu W, Matsumoto T, Ishikawa M, Nishimoto Y, Ishihara Y, Sakuma T, Yamamoto T, Tsuiji H, Suzuki N, Warita H, Aoki M, Okano H. Ichiyanagi N, et al. Among authors: okano h. Stem Cell Reports. 2016 Apr 12;6(4):496-510. doi: 10.1016/j.stemcr.2016.02.011. Epub 2016 Mar 17. Stem Cell Reports. 2016. PMID: 26997647 Free PMC article.
Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons.
Akiyama T, Suzuki N, Ishikawa M, Fujimori K, Sone T, Kawada J, Funayama R, Fujishima F, Mitsuzawa S, Ikeda K, Ono H, Shijo T, Osana S, Shirota M, Nakagawa T, Kitajima Y, Nishiyama A, Izumi R, Morimoto S, Okada Y, Kamei T, Nishida M, Nogami M, Kaneda S, Ikeuchi Y, Mitsuhashi H, Nakayama K, Fujii T, Warita H, Okano H, Aoki M. Akiyama T, et al. Among authors: okano h. EBioMedicine. 2019 Jul;45:362-378. doi: 10.1016/j.ebiom.2019.06.013. Epub 2019 Jun 29. EBioMedicine. 2019. PMID: 31262712 Free PMC article.
Ropinirole hydrochloride remedy for amyotrophic lateral sclerosis - Protocol for a randomized, double-blind, placebo-controlled, single-center, and open-label continuation phase I/IIa clinical trial (ROPALS trial).
Morimoto S, Takahashi S, Fukushima K, Saya H, Suzuki N, Aoki M, Okano H, Nakahara J. Morimoto S, et al. Among authors: okano h. Regen Ther. 2019 Jul 26;11:143-166. doi: 10.1016/j.reth.2019.07.002. eCollection 2019 Dec. Regen Ther. 2019. PMID: 31384636 Free PMC article.
[Ropinirole Hydrochloride for ALS].
Takahashi S, Morimoto S, Fukushima K, Nakahara J, Okano H. Takahashi S, et al. Among authors: okano h. Brain Nerve. 2019 Nov;71(11):1279-1288. doi: 10.11477/mf.1416201438. Brain Nerve. 2019. PMID: 31722314 Clinical Trial. Japanese.
1,696 results