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Fatty acid desaturase 2 determines the lipidomic landscape and steroidogenic function of the adrenal gland.
Witt A, Mateska I, Palladini A, Sinha A, Wölk M, Harauma A, Bechmann N, Pamporaki C, Dahl A, Rothe M, Kopaliani I, Adolf C, Riester A, Wielockx B, Bornstein SR, Kroiss M, Peitzsch M, Moriguchi T, Fedorova M, Grzybek M, Chavakis T, Mirtschink P, Alexaki VI. Witt A, et al. Among authors: kopaliani i. Sci Adv. 2023 Jul 21;9(29):eadf6710. doi: 10.1126/sciadv.adf6710. Epub 2023 Jul 21. Sci Adv. 2023. PMID: 37478183 Free PMC article.
Overexpression of dimethylarginine dimethylaminohydrolase 1 protects from angiotensin II-induced cardiac hypertrophy and vascular remodeling.
Kopaliani I, Jarzebska N, Billoff S, Kolouschek A, Martens-Lobenhoffer J, Bornstein SR, Bode-Böger SM, Ragavan VN, Weiss N, Mangoni AA, Deussen A, Rodionov RN. Kopaliani I, et al. Am J Physiol Heart Circ Physiol. 2021 Nov 1;321(5):H825-H838. doi: 10.1152/ajpheart.00064.2021. Epub 2021 Sep 17. Am J Physiol Heart Circ Physiol. 2021. PMID: 34533401 Free article.
Developmental endothelial locus-1 protects from hypertension-induced cardiovascular remodeling via immunomodulation.
Failer T, Amponsah-Offeh M, Neuwirth A, Kourtzelis I, Subramanian P, Mirtschink P, Peitzsch M, Matschke K, Tugtekin SM, Kajikawa T, Li X, Steglich A, Gembardt F, Wegner AC, Hugo C, Hajishengallis G, Chavakis T, Deussen A, Todorov V, Kopaliani I. Failer T, et al. Among authors: kopaliani i. J Clin Invest. 2022 Mar 15;132(6):e126155. doi: 10.1172/JCI126155. J Clin Invest. 2022. PMID: 35133978 Free PMC article.
Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction.
Klapproth E, Witt A, Klose P, Wiedemann J, Vavilthota N, Künzel SR, Kämmerer S, Günscht M, Sprott D, Lesche M, Rost F, Dahl A, Rauch E, Kattner L, Weber S, Mirtschink P, Kopaliani I, Guan K, Lorenz K, Saftig P, Wagner M, El-Armouche A. Klapproth E, et al. Among authors: kopaliani i. Nat Commun. 2022 Dec 10;13(1):7648. doi: 10.1038/s41467-022-35331-0. Nat Commun. 2022. PMID: 36496449 Free PMC article.
Estrogen determines sex differences in adrenergic vessel tone by regulation of endothelial β-adrenoceptor expression.
Riedel K, Deussen AJ, Tolkmitt J, Weber S, Schlinkert P, Zatschler B, Friebel C, Müller B, El-Armouche A, Morawietz H, Matschke K, Kopaliani I. Riedel K, et al. Among authors: kopaliani i. Am J Physiol Heart Circ Physiol. 2019 Aug 1;317(2):H243-H254. doi: 10.1152/ajpheart.00456.2018. Epub 2019 May 31. Am J Physiol Heart Circ Physiol. 2019. PMID: 31149843 Free article.
Targeting inflammation in hypertension.
Deussen A, Kopaliani I. Deussen A, et al. Among authors: kopaliani i. Curr Opin Nephrol Hypertens. 2023 Mar 1;32(2):111-117. doi: 10.1097/MNH.0000000000000862. Epub 2022 Dec 7. Curr Opin Nephrol Hypertens. 2023. PMID: 36476561 Free PMC article. Review.
Induction of Heme Oxygenase-1 Is Linked to the Severity of Disease in Human Abdominal Aortic Aneurysm.
Hofmann A, Müglich M, Wolk S, Khorzom Y, Sabarstinski P, Kopaliani I, Egorov D, Horn F, Brunssen C, Giebe S, Hamann B, Deussen A, Morawietz H, Poitz DM, Reeps C. Hofmann A, et al. Among authors: kopaliani i. J Am Heart Assoc. 2021 Oct 19;10(20):e022747. doi: 10.1161/JAHA.121.022747. Epub 2021 Oct 8. J Am Heart Assoc. 2021. PMID: 34622673 Free PMC article.
23 results