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183 results

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Neurotensin Analogues Containing Cyclic Surrogates of Tyrosine at Position 11 Improve NTS2 Selectivity Leading to Analgesia without Hypotension and Hypothermia.
Eiselt E, Gonzalez S, Martin C, Chartier M, Betti C, Longpré JM, Cavelier F, Tourwé D, Gendron L, Ballet S, Sarret P. Eiselt E, et al. Among authors: ballet s. ACS Chem Neurosci. 2019 Nov 20;10(11):4535-4544. doi: 10.1021/acschemneuro.9b00390. Epub 2019 Oct 21. ACS Chem Neurosci. 2019. PMID: 31589400
Optimized Opioid-Neurotensin Multitarget Peptides: From Design to Structure-Activity Relationship Studies.
Gonzalez S, Dumitrascuta M, Eiselt E, Louis S, Kunze L, Blasiol A, Vivancos M, Previti S, Dewolf E, Martin C, Tourwé D, Cavelier F, Gendron L, Sarret P, Spetea M, Ballet S. Gonzalez S, et al. Among authors: ballet s. J Med Chem. 2020 Nov 12;63(21):12929-12941. doi: 10.1021/acs.jmedchem.0c01376. Epub 2020 Sep 23. J Med Chem. 2020. PMID: 32902268 Free PMC article.
Structure-Based Design of Melanocortin 4 Receptor Ligands Based on the SHU-9119-hMC4R Cocrystal Structure†.
Martin C, Gimenez LE, Williams SY, Jing Y, Wu Y, Hollanders C, Van der Poorten O, Gonzalez S, Van Holsbeeck K, Previti S, Lamouroux A, Zhao S, Tourwé D, Stevens RC, Cone RD, Ballet S. Martin C, et al. Among authors: ballet s. J Med Chem. 2021 Jan 14;64(1):357-369. doi: 10.1021/acs.jmedchem.0c01620. Epub 2020 Nov 14. J Med Chem. 2021. PMID: 33190475
Nanobody Loop Mimetics Enhance Son of Sevenless 1-Catalyzed Nucleotide Exchange on RAS.
Van Holsbeeck K, Fischer B, Gonzalez S, Gadais C, Versées W, Martins JC, Martin C, Wohlkönig A, Steyaert J, Ballet S. Van Holsbeeck K, et al. Among authors: ballet s. Angew Chem Int Ed Engl. 2023 Jun 12;62(24):e202219095. doi: 10.1002/anie.202219095. Epub 2023 May 5. Angew Chem Int Ed Engl. 2023. PMID: 37067463
Multitarget μ-Opioid Receptor Agonists─Neuropeptide FF Receptor Antagonists Induce Potent Antinociception with Reduced Adverse Side Effects.
De Neve J, Elhabazi K, Gonzalez S, Herby C, Schneider S, Utard V, Fellmann-Clauss R, Petit-Demouliere N, Lecat S, Kremer M, Ces A, Daubeuf F, Martin C, Ballet S, Bihel F, Simonin F. De Neve J, et al. Among authors: ballet s. J Med Chem. 2024 May 9;67(9):7603-7619. doi: 10.1021/acs.jmedchem.4c00442. Epub 2024 Apr 30. J Med Chem. 2024. PMID: 38687204
Allosteric nanobodies to study the interactions between SOS1 and RAS.
Fischer B, Uchański T, Sheryazdanova A, Gonzalez S, Volkov AN, Brosens E, Zögg T, Kalichuk V, Ballet S, Versées W, Sablina AA, Pardon E, Wohlkönig A, Steyaert J. Fischer B, et al. Among authors: ballet s. Nat Commun. 2024 Jul 23;15(1):6214. doi: 10.1038/s41467-024-50349-2. Nat Commun. 2024. PMID: 39043660 Free PMC article.
183 results