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Design, Synthesis and Structure-Activity Relationships of Phenylalanine-Containing Peptidomimetics as Novel HIV-1 Capsid Binders Based on Ugi Four-Component Reaction.
Ji X, Li J, Sharma PP, Jiang X, Rathi B, Gao Z, Hu L, Kang D, De Clercq E, Cocklin S, Liu C, Pannecouque C, Dick A, Liu X, Zhan P. Ji X, et al. Among authors: liu x, liu c. Molecules. 2022 Sep 14;27(18):5995. doi: 10.3390/molecules27185995. Molecules. 2022. PMID: 36144727 Free PMC article.
Discovery of N-substituted oseltamivir derivatives as novel neuraminidase inhibitors with improved drug resistance profiles and favorable drug-like properties.
Jia R, Zhang J, Shi F, Bonomini A, Lucca C, Bertagnin C, Zhang J, Liu C, Jia H, Jiang Y, Ma X, Loregian A, Huang B, Zhan P, Liu X. Jia R, et al. Among authors: liu x, liu c. Eur J Med Chem. 2023 Apr 5;252:115275. doi: 10.1016/j.ejmech.2023.115275. Epub 2023 Mar 13. Eur J Med Chem. 2023. PMID: 36931117
A novel N-heterocycles substituted oseltamivir derivatives as potent inhibitors of influenza virus neuraminidase: discovery, synthesis and biological evaluation.
Zhang J, Liu C, Jia R, Zhang X, Zhang J, Bertagnin C, Bonomini A, Guizzo L, Jiang Y, Jia H, Jia S, Ma X, Loregian A, Huang B, Zhan P, Liu X. Zhang J, et al. Among authors: liu x, liu c. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2277135. doi: 10.1080/14756366.2023.2277135. Epub 2023 Nov 13. J Enzyme Inhib Med Chem. 2023. PMID: 37955306 Free PMC article.
Emerging drug design strategies in anti-influenza drug discovery.
Liu C, Hu L, Dong G, Zhang Y, Ferreira da Silva-Júnior E, Liu X, Menéndez-Arias L, Zhan P. Liu C, et al. Among authors: liu x. Acta Pharm Sin B. 2023 Dec;13(12):4715-4732. doi: 10.1016/j.apsb.2023.08.010. Epub 2023 Aug 14. Acta Pharm Sin B. 2023. PMID: 38045039 Free PMC article. Review.
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