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Page 1
Inhibition of WNT/β-catenin signalling during sex-specific gonadal differentiation is essential for normal human fetal testis development.
Lundgaard Riis M, Delpouve G, Nielsen JE, Melau C, Langhoff Thuesen L, Juul Hare K, Dreisler E, Aaboe K, Tutein Brenøe P, Albrethsen J, Frederiksen H, Juul A, Giacobini P, Jørgensen A. Lundgaard Riis M, et al. Among authors: langhoff thuesen l. Cell Commun Signal. 2024 Jun 15;22(1):330. doi: 10.1186/s12964-024-01704-9. Cell Commun Signal. 2024. PMID: 38879537 Free PMC article.
Dexamethasone affects human fetal adrenal steroidogenesis and subsequent ACTH response in an ex vivo culture model.
Melau C, Gayete Mor B, Lundgaard Riis M, Nielsen JE, Dreisler E, Aaboe K, Tutein Brenøe P, Langhoff Thuesen L, Juul Hare K, Mitchell RT, Frederiksen H, Juul A, Jørgensen A. Melau C, et al. Among authors: langhoff thuesen l. Front Endocrinol (Lausanne). 2023 Jul 6;14:1114211. doi: 10.3389/fendo.2023.1114211. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37484942 Free PMC article.
Identification of a window of androgen sensitivity for somatic cell function in human fetal testis cultured ex vivo.
Lundgaard Riis M, Matilionyte G, Nielsen JE, Melau C, Greenald D, Juul Hare K, Langhoff Thuesen L, Dreisler E, Aaboe K, Brenøe PT, Andersson AM, Albrethsen J, Frederiksen H, Rajpert-De Meyts E, Juul A, Mitchell RT, Jørgensen A. Lundgaard Riis M, et al. Among authors: langhoff thuesen l. BMC Med. 2022 Oct 20;20(1):399. doi: 10.1186/s12916-022-02602-y. BMC Med. 2022. PMID: 36266662 Free PMC article.
Dysregulation of FGFR signalling by a selective inhibitor reduces germ cell survival in human fetal gonads of both sexes and alters the somatic niche in fetal testes.
Harpelunde Poulsen K, Nielsen JE, Frederiksen H, Melau C, Juul Hare K, Langhoff Thuesen L, Perlman S, Lundvall L, Mitchell RT, Juul A, Rajpert-De Meyts E, Jørgensen A. Harpelunde Poulsen K, et al. Among authors: langhoff thuesen l. Hum Reprod. 2019 Nov 1;34(11):2228-2243. doi: 10.1093/humrep/dez191. Hum Reprod. 2019. PMID: 31734698 Free PMC article.
Characterization of Human Adrenal Steroidogenesis During Fetal Development.
Melau C, Nielsen JE, Frederiksen H, Kilcoyne K, Perlman S, Lundvall L, Langhoff Thuesen L, Juul Hare K, Andersson AM, Mitchell RT, Juul A, Jørgensen A. Melau C, et al. Among authors: langhoff thuesen l. J Clin Endocrinol Metab. 2019 May 1;104(5):1802-1812. doi: 10.1210/jc.2018-01759. J Clin Endocrinol Metab. 2019. PMID: 30590593 Free PMC article.
Nodal Signaling Regulates Germ Cell Development and Establishment of Seminiferous Cords in the Human Fetal Testis.
Jørgensen A, Macdonald J, Nielsen JE, Kilcoyne KR, Perlman S, Lundvall L, Langhoff Thuesen L, Juul Hare K, Frederiksen H, Andersson AM, Skakkebæk NE, Juul A, Sharpe RM, Rajpert-De Meyts E, Mitchell RT. Jørgensen A, et al. Among authors: langhoff thuesen l. Cell Rep. 2018 Nov 13;25(7):1924-1937.e4. doi: 10.1016/j.celrep.2018.10.064. Cell Rep. 2018. PMID: 30428358 Free article.