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Increased beta2-adrenergic signaling is a targetable stimulus essential for bone healing by promoting callus neovascularization.
Jahn D, Knapstein PR, Otto E, Köhli P, Sevecke J, Graef F, Graffmann C, Fuchs M, Jiang S, Rickert M, Erdmann C, Appelt J, Revend L, Küttner Q, Witte J, Rahmani A, Duda G, Xie W, Donat A, Schinke T, Ivanov A, Tchouto MN, Beule D, Frosch KH, Baranowsky A, Tsitsilonis S, Keller J. Jahn D, et al. Among authors: duda g. bioRxiv [Preprint]. 2023 Jul 16:2023.07.14.548550. doi: 10.1101/2023.07.14.548550. bioRxiv. 2023. Update in: Sci Transl Med. 2024 Apr 17;16(743):eadk9129. doi: 10.1126/scitranslmed.adk9129 PMID: 37502964 Free PMC article. Updated. Preprint.
The haematoma and its role in bone healing.
Schell H, Duda GN, Peters A, Tsitsilonis S, Johnson KA, Schmidt-Bleek K. Schell H, et al. Among authors: duda gn. J Exp Orthop. 2017 Dec;4(1):5. doi: 10.1186/s40634-017-0079-3. Epub 2017 Feb 7. J Exp Orthop. 2017. PMID: 28176273 Free PMC article. Review.
The neuropeptide calcitonin gene-related peptide alpha is essential for bone healing.
Appelt J, Baranowsky A, Jahn D, Yorgan T, Köhli P, Otto E, Farahani SK, Graef F, Fuchs M, Herrera A, Amling M, Schinke T, Frosch KH, Duda GN, Tsitsilonis S, Keller J. Appelt J, et al. EBioMedicine. 2020 Sep;59:102970. doi: 10.1016/j.ebiom.2020.102970. Epub 2020 Aug 24. EBioMedicine. 2020. PMID: 32853990 Free PMC article.
605 results