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Aster-dependent non-vesicular transport facilitates dietary cholesterol uptake.
Ferrari A, Whang E, Xiao X, Kennelly JP, Romartinez-Alonso B, Mack JJ, Weston T, Chen K, Kim Y, Tol MJ, Bideyan L, Nguyen A, Gao Y, Cui L, Bedard AH, Sandhu J, Lee SD, Fairall L, Williams KJ, Song W, Munguia P, Russell RA, Martin MG, Jung ME, Jiang H, Schwabe JWR, Young SG, Tontonoz P. Ferrari A, et al. Among authors: tontonoz p. bioRxiv [Preprint]. 2023 Jul 10:2023.07.07.548168. doi: 10.1101/2023.07.07.548168. bioRxiv. 2023. Update in: Science. 2023 Nov 10;382(6671):eadf0966. doi: 10.1126/science.adf0966 PMID: 37503112 Free PMC article. Updated. Preprint.
Low MBOAT7 expression, a genetic risk for MASH, promotes a profibrotic pathway involving hepatocyte TAZ upregulation.
Moore MP, Wang X, Kennelly JP, Shi H, Ishino Y, Kano K, Aoki J, Cherubini A, Ronzoni L, Guo X, Chalasani NP, Khalid S, Saleheen D, Mitsche MA, Rotter JI, Yates KP, Valenti L, Kono N, Tontonoz P, Tabas I. Moore MP, et al. Among authors: tontonoz p. Hepatology. 2024 May 22. doi: 10.1097/HEP.0000000000000933. Online ahead of print. Hepatology. 2024. PMID: 38776184
PPARγ-dependent remodeling of translational machinery in adipose progenitors is impaired in obesity.
De Siqueira MK, Li G, Zhao Y, Wang S, Ahn IS, Tamboline M, Hildreth AD, Larios J, Schcolnik-Cabrera A, Nouhi Z, Zhang Z, Tol MJ, Pandey V, Xu S, O'Sullivan TE, Mack JJ, Tontonoz P, Sallam T, Wohlschlegel JA, Hulea L, Xiao X, Yang X, Villanueva CJ. De Siqueira MK, et al. Among authors: tontonoz p. Cell Rep. 2024 Dec 24;43(12):114945. doi: 10.1016/j.celrep.2024.114945. Epub 2024 Nov 22. Cell Rep. 2024. PMID: 39579770 Free article.
Dietary control of peripheral adipose storage capacity through membrane lipid remodelling.
Tol MJ, Shimanaka Y, Bedard AH, Sapia J, Cui L, Colaço-Gaspar M, Hofer P, Ferrari A, Qian K, Kennelly JP, Lee SD, Gao Y, Xiao X, Gao J, Mack JJ, Weston TA, Pan C, Lusis AJ, Williams KJ, Su B, Pike DP, Reed A, Milosevich N, Cravatt BF, Arita M, Young SG, Ford DA, Zechner R, Vanni S, Tontonoz P. Tol MJ, et al. Among authors: tontonoz p. bioRxiv [Preprint]. 2024 Oct 29:2024.10.25.620374. doi: 10.1101/2024.10.25.620374. bioRxiv. 2024. PMID: 39554041 Free PMC article. Preprint.
273 results