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Ebola Virus VP35 Interacts Non-Covalently with Ubiquitin Chains to Promote Viral Replication Creating New Therapeutic Opportunities.
Rodríguez-Salazar CA, van Tol S, Mailhot O, Galdino G, Teruel N, Zhang L, Warren AN, González-Orozco M, Freiberg AN, Najmanovich RJ, Giraldo MI, Rajsbaum R. Rodríguez-Salazar CA, et al. Among authors: najmanovich rj. bioRxiv [Preprint]. 2023 Jul 15:2023.07.14.549057. doi: 10.1101/2023.07.14.549057. bioRxiv. 2023. Update in: PLoS Biol. 2024 Feb 29;22(2):e3002544. doi: 10.1371/journal.pbio.3002544 PMID: 37503276 Free PMC article. Updated. Preprint.
Ebola virus VP35 interacts non-covalently with ubiquitin chains to promote viral replication.
Rodríguez-Salazar CA, van Tol S, Mailhot O, Gonzalez-Orozco M, Galdino GT, Warren AN, Teruel N, Behera P, Afreen KS, Zhang L, Juelich TL, Smith JK, Zylber MI, Freiberg AN, Najmanovich RJ, Giraldo MI, Rajsbaum R. Rodríguez-Salazar CA, et al. Among authors: najmanovich rj. PLoS Biol. 2024 Feb 29;22(2):e3002544. doi: 10.1371/journal.pbio.3002544. eCollection 2024 Feb. PLoS Biol. 2024. PMID: 38422166 Free PMC article.
TRIM7 ubiquitinates SARS-CoV-2 membrane protein to limit apoptosis and viral replication.
Gonzalez-Orozco M, Tseng HC, Hage A, Xia H, Behera P, Afreen K, Peñaflor-Tellez Y, Giraldo MI, Huante M, Puebla-Clark L, van Tol S, Odle A, Crown M, Teruel N, Shelite TR, Moreno-Contreras J, Terasaki K, Makino S, Menachery V, Endsley M, Endsley JJ, Najmanovich RJ, Bashton M, Stephens R, Shi PY, Xie X, Freiberg AN, Rajsbaum R. Gonzalez-Orozco M, et al. Among authors: najmanovich rj. Nat Commun. 2024 Nov 30;15(1):10438. doi: 10.1038/s41467-024-54762-5. Nat Commun. 2024. PMID: 39616206 Free PMC article.
TRIM7 ubiquitinates SARS-CoV-2 membrane protein to limit apoptosis and viral replication.
Gonzalez-Orozco M, Tseng HC, Hage A, Xia H, Behera P, Afreen K, Peñaflor-Tellez Y, Giraldo MI, Huante M, Puebla-Clark L, van Tol S, Odle A, Crown M, Teruel N, Shelite TR, Menachery V, Endsley M, Endsley JJ, Najmanovich RJ, Bashton M, Stephens R, Shi PY, Xie X, Freiberg AN, Rajsbaum R. Gonzalez-Orozco M, et al. Among authors: najmanovich rj. bioRxiv [Preprint]. 2024 Jun 17:2024.06.17.599107. doi: 10.1101/2024.06.17.599107. bioRxiv. 2024. Update in: Nat Commun. 2024 Nov 30;15(1):10438. doi: 10.1038/s41467-024-54762-5 PMID: 38948778 Free PMC article. Updated. Preprint.
Modulating the selectivity of matriptase-2 inhibitors with unnatural amino acids.
St-Georges C, Désilets A, Béliveau F, Ghinet M, Dion SP, Colombo É, Boudreault PL, Najmanovich RJ, Leduc R, Marsault É. St-Georges C, et al. Among authors: najmanovich rj. Eur J Med Chem. 2017 Mar 31;129:110-123. doi: 10.1016/j.ejmech.2017.02.006. Epub 2017 Feb 11. Eur J Med Chem. 2017. PMID: 28219045
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