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Patients with naproxen-induced liver injury display T-cell memory responses toward an oxidative (S)-O-desmethyl naproxen metabolite but not the acyl glucuronide.
Thomson P, Fragkas N, Kafu LM, Aithal GP, Lucena MI, Terracciano L, Meng X, Pirmohamed M, Brees D, Kullak-Ublick GA, Odermatt A, Hammond T, Kammüller M, Naisbitt DJ. Thomson P, et al. Among authors: meng x. Allergy. 2024 Jan;79(1):200-214. doi: 10.1111/all.15830. Epub 2023 Jul 29. Allergy. 2024. PMID: 37515456 Free PMC article.
Characterization of the antigen specificity of T-cell clones from piperacillin-hypersensitive patients with cystic fibrosis.
El-Ghaiesh S, Monshi MM, Whitaker P, Jenkins R, Meng X, Farrell J, Elsheikh A, Peckham D, French N, Pirmohamed M, Park BK, Naisbitt DJ. El-Ghaiesh S, et al. Among authors: meng x. J Pharmacol Exp Ther. 2012 Jun;341(3):597-610. doi: 10.1124/jpet.111.190900. Epub 2012 Feb 27. J Pharmacol Exp Ther. 2012. PMID: 22371438 Free PMC article.
β-Lactam antibiotics form distinct haptenic structures on albumin and activate drug-specific T-lymphocyte responses in multiallergic patients with cystic fibrosis.
Jenkins RE, Yaseen FS, Monshi MM, Whitaker P, Meng X, Farrell J, Hamlett J, Sanderson JP, El-Ghaiesh S, Peckham D, Pirmohamed M, Park BK, Naisbitt DJ. Jenkins RE, et al. Among authors: meng x. Chem Res Toxicol. 2013 Jun 17;26(6):963-75. doi: 10.1021/tx400124m. Epub 2013 May 23. Chem Res Toxicol. 2013. PMID: 23668298
Mass spectrometric characterization of circulating covalent protein adducts derived from a drug acyl glucuronide metabolite: multiple albumin adductions in diclofenac patients.
Hammond TG, Meng X, Jenkins RE, Maggs JL, Castelazo AS, Regan SL, Bennett SN, Earnshaw CJ, Aithal GP, Pande I, Kenna JG, Stachulski AV, Park BK, Williams DP. Hammond TG, et al. Among authors: meng x. J Pharmacol Exp Ther. 2014 Aug;350(2):387-402. doi: 10.1124/jpet.114.215079. Epub 2014 Jun 5. J Pharmacol Exp Ther. 2014. PMID: 24902585 Free PMC article.
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