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2-hydroxyglutarate rides the cancer-immunity cycle.
Foskolou IP, Bunse L, Van den Bossche J. Foskolou IP, et al. Among authors: van den bossche j. Curr Opin Biotechnol. 2023 Oct;83:102976. doi: 10.1016/j.copbio.2023.102976. Epub 2023 Jul 27. Curr Opin Biotechnol. 2023. PMID: 37515937 Free article. Review.
d-2-Hydroxyglutarate is an anti-inflammatory immunometabolite that accumulates in macrophages after TLR4 activation.
de Goede KE, Harber KJ, Gorki FS, Verberk SGS, Groh LA, Keuning ED, Struys EA, van Weeghel M, Haschemi A, de Winther MPJ, van Dierendonck XAMH, Van den Bossche J. de Goede KE, et al. Among authors: van weeghel m, van den bossche j, van dierendonck xamh. Biochim Biophys Acta Mol Basis Dis. 2022 Sep 1;1868(9):166427. doi: 10.1016/j.bbadis.2022.166427. Epub 2022 May 6. Biochim Biophys Acta Mol Basis Dis. 2022. PMID: 35526742 Free article.
Single-cell metabolic profiling of human cytotoxic T cells.
Hartmann FJ, Mrdjen D, McCaffrey E, Glass DR, Greenwald NF, Bharadwaj A, Khair Z, Verberk SGS, Baranski A, Baskar R, Graf W, Van Valen D, Van den Bossche J, Angelo M, Bendall SC. Hartmann FJ, et al. Among authors: van den bossche j, van valen d. Nat Biotechnol. 2021 Feb;39(2):186-197. doi: 10.1038/s41587-020-0651-8. Epub 2020 Aug 31. Nat Biotechnol. 2021. PMID: 32868913 Free PMC article.
Let's Enter the Wonderful World of Immunometabolites.
de Goede KE, Harber KJ, Van den Bossche J. de Goede KE, et al. Among authors: van den bossche j. Trends Endocrinol Metab. 2019 Jun;30(6):329-331. doi: 10.1016/j.tem.2019.03.004. Epub 2019 May 3. Trends Endocrinol Metab. 2019. PMID: 31060882
Succinate Is an Inflammation-Induced Immunoregulatory Metabolite in Macrophages.
Harber KJ, de Goede KE, Verberk SGS, Meinster E, de Vries HE, van Weeghel M, de Winther MPJ, Van den Bossche J. Harber KJ, et al. Among authors: van weeghel m, van den bossche j. Metabolites. 2020 Sep 15;10(9):372. doi: 10.3390/metabo10090372. Metabolites. 2020. PMID: 32942769 Free PMC article.
Immunometabolism at the basis of health and disease; an editorial.
Van den Bossche J, Horng T, Ryan DG. Van den Bossche J, et al. Biochim Biophys Acta Mol Basis Dis. 2023 Aug;1869(6):166715. doi: 10.1016/j.bbadis.2023.166715. Epub 2023 Apr 6. Biochim Biophys Acta Mol Basis Dis. 2023. PMID: 37030523 Free article. No abstract available.
148 results