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Page 1
Brain plasticity and neuroinflammatory protein biomarkers with circulating MicroRNAs as predictors of acute brain injury outcome - A prospective cohort study.
Sajanti A, Li Y, Hellström S, Cao Y, Girard R, Umemori J, Frantzén J, Koskimäki F, Lyne SB, Falter J, Rantamäki T, Takala R, Posti JP, Roine S, Kolehmainen S, Srinath A, Jänkälä M, Puolitaival J, Rahi M, Rinne J, Castrén E, Koskimäki J. Sajanti A, et al. Among authors: umemori j. J Neurol Sci. 2024 Sep 15;464:123169. doi: 10.1016/j.jns.2024.123169. Epub 2024 Aug 8. J Neurol Sci. 2024. PMID: 39126731 Free article.
A small TAT-TrkB peptide prevents BDNF receptor cleavage and restores synaptic physiology in Alzheimer's disease.
Fonseca-Gomes J, Costa-Coelho T, Ferreira-Manso M, Inteiro-Oliveira S, Vaz SH, Alemãn-Serrano N, Atalaia-Barbacena H, Ribeiro-Rodrigues L, Ramalho RM, Pinto R, Miranda HV, Tanqueiro SR, de Almeida-Borlido C, Ramalho MJ, Miranda-Lourenço C, Belo RF, Ferreira CB, Neves V, Rombo DM, Viais R, Umemori J, Martins IC, Jerónimo-Santos A, Caetano A, Manso N, Mäkinen P, Marttinen M, Takalo M, Bremang M, Pike I, Haapasalo A, Loureiro JA, Pereira MC, Santos NC, Outeiro TF, Castanho MARB, Fernandes A, Hiltunen M, Duarte CB, Castrén E, de Mendonça A, Sebastião AM, Rodrigues TM, Diógenes MJ. Fonseca-Gomes J, et al. Among authors: umemori j. Mol Ther. 2024 Dec 12:S1525-0016(24)00804-9. doi: 10.1016/j.ymthe.2024.12.005. Online ahead of print. Mol Ther. 2024. PMID: 39672159 No abstract available.
Activation of TrkB in Parvalbumin interneurons is required for the promotion of reversal learning in spatial and fear memory by antidepressants.
Jetsonen E, Didio G, Winkel F, Llach Pou M, Boj C, Kuczynski-Noyau L, Võikar V, Guirado R, Taira T, Lauri SE, Castrén E, Umemori J. Jetsonen E, et al. Among authors: umemori j. Neuropsychopharmacology. 2023 Jun;48(7):1021-1030. doi: 10.1038/s41386-023-01562-y. Epub 2023 Mar 21. Neuropsychopharmacology. 2023. PMID: 36944718 Free PMC article.
BDNF receptor TrkB as the mediator of the antidepressant drug action.
Casarotto P, Umemori J, Castrén E. Casarotto P, et al. Among authors: umemori j. Front Mol Neurosci. 2022 Nov 2;15:1032224. doi: 10.3389/fnmol.2022.1032224. eCollection 2022. Front Mol Neurosci. 2022. PMID: 36407765 Free PMC article. Review.
Pharmacological and optical activation of TrkB in Parvalbumin interneurons regulate intrinsic states to orchestrate cortical plasticity.
Winkel F, Ryazantseva M, Voigt MB, Didio G, Lilja A, Llach Pou M, Steinzeig A, Harkki J, Englund J, Khirug S, Rivera C, Palva S, Taira T, Lauri SE, Umemori J, Castrén E. Winkel F, et al. Among authors: umemori j. Mol Psychiatry. 2021 Dec;26(12):7247-7256. doi: 10.1038/s41380-021-01211-0. Epub 2021 Jul 28. Mol Psychiatry. 2021. PMID: 34321594 Free PMC article.
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