Vocadlo DJ - Search Results

1

A Fluorogenic Disaccharide Substrate for α-Mannosidases Enables High-Throughput Screening and Identification of an Inhibitor of the GH92 Virulence Factor from Streptococcus pneumoniae.

Bhosale S, Deen MC, Proceviat C, Hettle A, Winter DK, Brockerman J, Levene M, Bennet AJ, Spino C, Boraston AB, Vocadlo DJ. Bhosale S, et al. Among authors: vocadlo dj. ACS Chem Biol. 2023 Aug 18;18(8):1730-1737. doi: 10.1021/acschembio.3c00053. Epub 2023 Aug 2. ACS Chem Biol. 2023. PMID: 37531094

2

Structural and mechanistic insight into the basis of mucopolysaccharidosis IIIB.

Ficko-Blean E, Stubbs KA, Nemirovsky O, Vocadlo DJ, Boraston AB. Ficko-Blean E, et al. Among authors: vocadlo dj. Proc Natl Acad Sci U S A. 2008 May 6;105(18):6560-5. doi: 10.1073/pnas.0711491105. Epub 2008 Apr 28. Proc Natl Acad Sci U S A. 2008. PMID: 18443291 Free PMC article.

3

Streptococcus pneumoniae endohexosaminidase D, structural and mechanistic insight into substrate-assisted catalysis in family 85 glycoside hydrolases.

Abbott DW, Macauley MS, Vocadlo DJ, Boraston AB. Abbott DW, et al. Among authors: vocadlo dj. J Biol Chem. 2009 Apr 24;284(17):11676-89. doi: 10.1074/jbc.M809663200. Epub 2009 Jan 30. J Biol Chem. 2009. PMID: 19181667 Free PMC article.

4

Differential recognition and hydrolysis of host carbohydrate antigens by Streptococcus pneumoniae family 98 glycoside hydrolases.

Higgins MA, Whitworth GE, El Warry N, Randriantsoa M, Samain E, Burke RD, Vocadlo DJ, Boraston AB. Higgins MA, et al. Among authors: vocadlo dj. J Biol Chem. 2009 Sep 18;284(38):26161-73. doi: 10.1074/jbc.M109.024067. Epub 2009 Jul 16. J Biol Chem. 2009. PMID: 19608744 Free PMC article.

5

Streptococcus pneumoniae endohexosaminidase D; feasibility of using N-glycan oxazoline donors for synthetic glycosylation of a GlcNAc-asparagine acceptor.

Parsons TB, Patel MK, Boraston AB, Vocadlo DJ, Fairbanks AJ. Parsons TB, et al. Among authors: vocadlo dj. Org Biomol Chem. 2010 Apr 21;8(8):1861-9. doi: 10.1039/b926078a. Org Biomol Chem. 2010. PMID: 20449490

6

Analysis of a new family of widely distributed metal-independent alpha-mannosidases provides unique insight into the processing of N-linked glycans.

Gregg KJ, Zandberg WF, Hehemann JH, Whitworth GE, Deng L, Vocadlo DJ, Boraston AB. Gregg KJ, et al. Among authors: vocadlo dj. J Biol Chem. 2011 Apr 29;286(17):15586-96. doi: 10.1074/jbc.M111.223172. Epub 2011 Mar 9. J Biol Chem. 2011. PMID: 21388958 Free PMC article.

7

The conformation and function of a multimodular glycogen-degrading pneumococcal virulence factor.

Lammerts van Bueren A, Ficko-Blean E, Pluvinage B, Hehemann JH, Higgins MA, Deng L, Ogunniyi AD, Stroeher UH, El Warry N, Burke RD, Czjzek M, Paton JC, Vocadlo DJ, Boraston AB. Lammerts van Bueren A, et al. Among authors: vocadlo dj. Structure. 2011 May 11;19(5):640-51. doi: 10.1016/j.str.2011.03.001. Structure. 2011. PMID: 21565699 Free article.

8

Inhibition of the pneumococcal virulence factor StrH and molecular insights into N-glycan recognition and hydrolysis.

Pluvinage B, Higgins MA, Abbott DW, Robb C, Dalia AB, Deng L, Weiser JN, Parsons TB, Fairbanks AJ, Vocadlo DJ, Boraston AB. Pluvinage B, et al. Among authors: vocadlo dj. Structure. 2011 Nov 9;19(11):1603-14. doi: 10.1016/j.str.2011.08.011. Structure. 2011. PMID: 22078560 Free article.

9

Analysis of keystone enzyme in Agar hydrolysis provides insight into the degradation (of a polysaccharide from) red seaweeds.

Hehemann JH, Smyth L, Yadav A, Vocadlo DJ, Boraston AB. Hehemann JH, et al. Among authors: vocadlo dj. J Biol Chem. 2012 Apr 20;287(17):13985-95. doi: 10.1074/jbc.M112.345645. Epub 2012 Mar 5. J Biol Chem. 2012. PMID: 22393053 Free PMC article.

10

Metabolism of vertebrate amino sugars with N-glycolyl groups: intracellular β-O-linked N-glycolylglucosamine (GlcNGc), UDP-GlcNGc, and the biochemical and structural rationale for the substrate tolerance of β-O-linked β-N-acetylglucosaminidase.

Macauley MS, Chan J, Zandberg WF, He Y, Whitworth GE, Stubbs KA, Yuzwa SA, Bennet AJ, Varki A, Davies GJ, Vocadlo DJ. Macauley MS, et al. Among authors: vocadlo dj. J Biol Chem. 2012 Aug 17;287(34):28882-97. doi: 10.1074/jbc.M112.363721. Epub 2012 Jun 12. J Biol Chem. 2012. PMID: 22692202 Free PMC article.

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