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527 results

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Page 1
DNA-encoded chemical libraries yield non-covalent and non-peptidic SARS-CoV-2 main protease inhibitors.
Jimmidi R, Chamakuri S, Lu S, Ucisik MN, Chen PJ, Bohren KM, Moghadasi SA, Versteeg L, Nnabuife C, Li JY, Qin X, Chen YC, Faver JC, Nyshadham P, Sharma KL, Sankaran B, Judge A, Yu Z, Li F, Pollet J, Harris RS, Matzuk MM, Palzkill T, Young DW. Jimmidi R, et al. Among authors: harris rs. Commun Chem. 2023 Aug 4;6(1):164. doi: 10.1038/s42004-023-00961-y. Commun Chem. 2023. PMID: 37542196 Free PMC article.
Evidence for an extraterrestrial impact 12,900 years ago that contributed to the megafaunal extinctions and the Younger Dryas cooling.
Firestone RB, West A, Kennett JP, Becker L, Bunch TE, Revay ZS, Schultz PH, Belgya T, Kennett DJ, Erlandson JM, Dickenson OJ, Goodyear AC, Harris RS, Howard GA, Kloosterman JB, Lechler P, Mayewski PA, Montgomery J, Poreda R, Darrah T, Hee SS, Smith AR, Stich A, Topping W, Wittke JH, Wolbach WS. Firestone RB, et al. Among authors: harris rs. Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16016-21. doi: 10.1073/pnas.0706977104. Epub 2007 Sep 27. Proc Natl Acad Sci U S A. 2007. PMID: 17901202 Free PMC article.
Regulatory interactions between APOBEC3B N- and C-terminal domains.
Braza MKE, Demir Ö, Ahn SH, Morris CK, Calvó-Tusell C, McGuire KL, de la Peña Avalos B, Carpenter MA, Chen Y, Casalino L, Aihara H, Herzik MA, Harris RS, Amaro RE. Braza MKE, et al. Among authors: harris rs. bioRxiv [Preprint]. 2024 Dec 12:2024.12.11.628032. doi: 10.1101/2024.12.11.628032. bioRxiv. 2024. PMID: 39713448 Free PMC article. Preprint.
Differentiation signals induce APOBEC3A expression via GRHL3 in squamous epithelia and squamous cell carcinoma.
Smith NJ, Reddin I, Policelli P, Oh S, Zainal N, Howes E, Jenkins B, Tracy I, Edmond M, Sharpe B, Amendra D, Zheng K, Egawa N, Doorbar J, Rao A, Mahadevan S, Carpenter MA, Harris RS, Ali S, Hanley C, Buisson R, King E, Thomas GJ, Fenton TR. Smith NJ, et al. Among authors: harris rs. EMBO J. 2024 Nov 15. doi: 10.1038/s44318-024-00298-9. Online ahead of print. EMBO J. 2024. PMID: 39548236 Free article.
RADD: A real-time FRET-based biochemical assay for DNA deaminase studies.
Belica CA, Hernandez PC, Carpenter MA, Chen Y, Brown WL, Harris RS, Aihara H. Belica CA, et al. Among authors: harris rs. Methods Enzymol. 2024;705:311-345. doi: 10.1016/bs.mie.2024.08.001. Epub 2024 Aug 27. Methods Enzymol. 2024. PMID: 39389668 Free PMC article.
A comprehensive study of SARS-CoV-2 main protease (Mpro) inhibitor-resistant mutants selected in a VSV-based system.
Costacurta F, Dodaro A, Bante D, Schöppe H, Peng JY, Sprenger B, He X, Moghadasi SA, Egger LM, Fleischmann J, Pavan M, Bassani D, Menin S, Rauch S, Krismer L, Sauerwein A, Heberle A, Rabensteiner T, Ho J, Harris RS, Stefan E, Schneider R, Dunzendorfer-Matt T, Naschberger A, Wang D, Kaserer T, Moro S, von Laer D, Heilmann E. Costacurta F, et al. Among authors: harris rs. PLoS Pathog. 2024 Sep 11;20(9):e1012522. doi: 10.1371/journal.ppat.1012522. eCollection 2024 Sep. PLoS Pathog. 2024. PMID: 39259728 Free PMC article.
SARS-CoV-2 Mpro inhibitor identification using a cellular gain-of-signal assay for high-throughput screening.
Delgado R, Vishwakarma J, Moghadasi SA, Otsuka Y, Shumate J, Cuell A, Tansiongco M, Cooley CB, Chen Y, Dabrowska A, Basu R, Anindita PD, Luo D, Dosa PI, Harki DA, Bannister T, Scampavia L, Spicer TP, Harris RS. Delgado R, et al. Among authors: harris rs. SLAS Discov. 2024 Sep;29(6):100181. doi: 10.1016/j.slasd.2024.100181. Epub 2024 Aug 22. SLAS Discov. 2024. PMID: 39173830 Free PMC article.
527 results