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TMEM63 proteins function as monomeric high-threshold mechanosensitive ion channels.
Zheng W, Rawson S, Shen Z, Tamilselvan E, Smith HE, Halford J, Shen C, Murthy SE, Ulbrich MH, Sotomayor M, Fu TM, Holt JR. Zheng W, et al. Among authors: shen c, shen z. Neuron. 2023 Oct 18;111(20):3195-3210.e7. doi: 10.1016/j.neuron.2023.07.006. Epub 2023 Aug 4. Neuron. 2023. PMID: 37543036 Free PMC article.
PtuA and PtuB assemble into an inflammasome-like oligomer for anti-phage defense.
Li Y, Shen Z, Zhang M, Yang XY, Cleary SP, Xie J, Marathe IA, Kostelic M, Greenwald J, Rish AD, Wysocki VH, Chen C, Chen Q, Fu TM, Yu Y. Li Y, et al. Among authors: shen z. Nat Struct Mol Biol. 2024 Mar;31(3):413-423. doi: 10.1038/s41594-023-01172-8. Epub 2024 Jan 4. Nat Struct Mol Biol. 2024. PMID: 38177683
Molecular basis of Gabija anti-phage supramolecular assemblies.
Yang XY, Shen Z, Xie J, Greenwald J, Marathe I, Lin Q, Xie WJ, Wysocki VH, Fu TM. Yang XY, et al. Among authors: shen z. Nat Struct Mol Biol. 2024 Aug;31(8):1243-1250. doi: 10.1038/s41594-024-01283-w. Epub 2024 Apr 16. Nat Struct Mol Biol. 2024. PMID: 38627580 Free PMC article.
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