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127 results

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Page 1
Nuclear Focal Adhesion Kinase Protects against Cisplatin Stress in Ovarian Carcinoma.
Zhang Y, Ojalill M, Boyer A, Chen XL, Tahon E, Thivolle Lioux G, Xia M, Abbas M, Soylu HM, Flieder DB, Connolly DC, Molinolo AA, McHale MT, Stupack DG, Schlaepfer DD. Zhang Y, et al. Among authors: molinolo aa. Cancer Res Commun. 2024 Dec 1;4(12):3165-3179. doi: 10.1158/2767-9764.CRC-24-0382. Cancer Res Commun. 2024. PMID: 39585085 Free PMC article.
A genome-wide CRISPR screen reveals that antagonism of glutamine metabolism sensitizes head and neck squamous cell carcinoma to ferroptotic cell death.
Allevato MM, Trinh S, Koshizuka K, Nachmanson D, Nguyen TC, Yokoyama Y, Wu X, Andres A, Wang Z, Watrous J, Molinolo AA, Mali P, Harismendy O, Jain M, Wild R, Gutkind JS. Allevato MM, et al. Among authors: molinolo aa. Cancer Lett. 2024 Aug 28;598:217089. doi: 10.1016/j.canlet.2024.217089. Epub 2024 Jul 2. Cancer Lett. 2024. PMID: 38964731
High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma.
Arang N, Lubrano S, Ceribelli M, Rigiracciolo DC, Saddawi-Konefka R, Faraji F, Ramirez SI, Kim D, Tosto FA, Stevenson E, Zhou Y, Wang Z, Bogomolovas J, Molinolo AA, Swaney DL, Krogan NJ, Yang J, Coma S, Pachter JA, Aplin AE, Alessi DR, Thomas CJ, Gutkind JS. Arang N, et al. Among authors: molinolo aa. Cell Rep Med. 2023 Nov 21;4(11):101244. doi: 10.1016/j.xcrm.2023.101244. Epub 2023 Oct 18. Cell Rep Med. 2023. PMID: 37858338 Free PMC article.
A Network Landscape of HPVOPC Reveals Methylation Alterations as Significant Drivers of Gene Expression via an Immune-Mediated GPCR Signal.
Qualliotine JR, Nakagawa T, Rosenthal SB, Sadat S, Ballesteros-Merino C, Xu G, Mark A, Nasamran A, Gutkind JS, Fisch KM, Guo T, Fox BA, Khan Z, Molinolo AA, Califano JA. Qualliotine JR, et al. Among authors: molinolo aa. Cancers (Basel). 2023 Sep 1;15(17):4379. doi: 10.3390/cancers15174379. Cancers (Basel). 2023. PMID: 37686653 Free PMC article.
YAP-Driven Oral Epithelial Stem Cell Malignant Reprogramming at Single Cell Resolution.
Faraji F, Ramirez SI, Clubb L, Sato K, Burghi V, Hoang TS, Officer A, Anguiano Quiroz PY, Galloway WM, Mikulski Z, Medetgul-Ernar K, Marangoni P, Jones KB, Molinolo AA, Kim K, Sakaguchi K, Califano JA, Smith Q, Goren A, Klein OD, Tamayo P, Gutkind JS. Faraji F, et al. Among authors: molinolo aa. bioRxiv [Preprint]. 2024 Oct 21:2023.07.24.550427. doi: 10.1101/2023.07.24.550427. bioRxiv. 2024. PMID: 37546810 Free PMC article. Preprint.
Immunohistochemical Techniques for Phosphoproteins.
Sanz Ressel BL, Molinolo AA. Sanz Ressel BL, et al. Among authors: molinolo aa. Methods Mol Biol. 2023;2593:259-264. doi: 10.1007/978-1-0716-2811-9_17. Methods Mol Biol. 2023. PMID: 36513937
Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC.
Saddawi-Konefka R, O'Farrell A, Faraji F, Clubb L, Allevato MM, Jensen SM, Yung BS, Wang Z, Wu VH, Anang NA, Msari RA, Schokrpur S, Pietryga IF, Molinolo AA, Mesirov JP, Simon AB, Fox BA, Bui JD, Sharabi A, Cohen EEW, Califano JA, Gutkind JS. Saddawi-Konefka R, et al. Among authors: molinolo aa. Nat Commun. 2022 Jul 25;13(1):4298. doi: 10.1038/s41467-022-31941-w. Nat Commun. 2022. PMID: 35879302 Free PMC article.
Monomethyl auristatin antibody and peptide drug conjugates for trimodal cancer chemo-radio-immunotherapy.
Hingorani DV, Allevato MM, Camargo MF, Lesperance J, Quraishi MA, Aguilera J, Franiak-Pietryga I, Scanderbeg DJ, Wang Z, Molinolo AA, Alvarado D, Sharabi AB, Bui JD, Cohen EEW, Adams SR, Gutkind JS, Advani SJ. Hingorani DV, et al. Among authors: molinolo aa. Nat Commun. 2022 Jul 5;13(1):3869. doi: 10.1038/s41467-022-31601-z. Nat Commun. 2022. PMID: 35790753 Free PMC article.
Inhibition of mTOR signaling and clinical activity of metformin in oral premalignant lesions.
Gutkind JS, Molinolo AA, Wu X, Wang Z, Nachmanson D, Harismendy O, Alexandrov LB, Wuertz BR, Ondrey FG, Laronde D, Rock LD, Rosin M, Coffey C, Butler VD, Bengtson L, Hsu CH, Bauman JE, Hewitt SM, Cohen EE, Chow HS, Lippman SM, Szabo E. Gutkind JS, et al. Among authors: molinolo aa. JCI Insight. 2021 Sep 8;6(17):e147096. doi: 10.1172/jci.insight.147096. JCI Insight. 2021. PMID: 34255745 Free PMC article. Clinical Trial.
Progesterone promotes immunomodulation and tumor development in the murine mammary gland.
Werner LR, Gibson KA, Goodman ML, Helm DE, Walter KR, Holloran SM, Trinca GM, Hastings RC, Yang HH, Hu Y, Wei J, Lei G, Yang XY, Madan R, Molinolo AA, Markiewicz MA, Chalise P, Axelrod ML, Balko JM, Hunter KW, Hartman ZC, Lange CA, Hagan CR. Werner LR, et al. Among authors: molinolo aa. J Immunother Cancer. 2021 May;9(5):e001710. doi: 10.1136/jitc-2020-001710. J Immunother Cancer. 2021. PMID: 33958486 Free PMC article.
127 results