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Spatial and single-nucleus transcriptomic analysis of genetic and sporadic forms of Alzheimer's Disease.
Miyoshi E, Morabito S, Henningfield CM, Rahimzadeh N, Kiani Shabestari S, Das S, Michael N, Reese F, Shi Z, Cao Z, Scarfone V, Arreola MA, Lu J, Wright S, Silva J, Leavy K, Lott IT, Doran E, Yong WH, Shahin S, Perez-Rosendahl M, Head E, Green KN, Swarup V. Miyoshi E, et al. bioRxiv [Preprint]. 2023 Jul 26:2023.07.24.550282. doi: 10.1101/2023.07.24.550282. bioRxiv. 2023. Update in: Nat Genet. 2024 Dec;56(12):2704-2717. doi: 10.1038/s41588-024-01961-x PMID: 37546983 Free PMC article. Updated. Preprint.
Rogue gene networks gone awry in Alzheimer's disease.
Miyoshi E, Swarup V. Miyoshi E, et al. Neural Regen Res. 2021 Dec;16(12):2415-2416. doi: 10.4103/1673-5374.313032. Neural Regen Res. 2021. PMID: 33907024 Free PMC article. Review. No abstract available.
Absence of microglia promotes diverse pathologies and early lethality in Alzheimer's disease mice.
Kiani Shabestari S, Morabito S, Danhash EP, McQuade A, Sanchez JR, Miyoshi E, Chadarevian JP, Claes C, Coburn MA, Hasselmann J, Hidalgo J, Tran KN, Martini AC, Chang Rothermich W, Pascual J, Head E, Hume DA, Pridans C, Davtyan H, Swarup V, Blurton-Jones M. Kiani Shabestari S, et al. Among authors: miyoshi e. Cell Rep. 2022 Jun 14;39(11):110961. doi: 10.1016/j.celrep.2022.110961. Cell Rep. 2022. PMID: 35705056 Free PMC article.
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation.
Lim RG, Al-Dalahmah O, Wu J, Gold MP, Reidling JC, Tang G, Adam M, Dansu DK, Park HJ, Casaccia P, Miramontes R, Reyes-Ortiz AM, Lau A, Hickman RA, Khan F, Paryani F, Tang A, Ofori K, Miyoshi E, Michael N, McClure N, Flowers XE, Vonsattel JP, Davidson S, Menon V, Swarup V, Fraenkel E, Goldman JE, Thompson LM. Lim RG, et al. Among authors: miyoshi e. Nat Commun. 2022 Dec 21;13(1):7791. doi: 10.1038/s41467-022-35388-x. Nat Commun. 2022. PMID: 36543778 Free PMC article.
Single-nuclei transcriptome analysis of Huntington disease iPSC and mouse astrocytes implicates maturation and functional deficits.
Reyes-Ortiz AM, Abud EM, Burns MS, Wu J, Hernandez SJ, McClure N, Wang KQ, Schulz CJ, Miramontes R, Lau A, Michael N, Miyoshi E, Van Vactor D, Reidling JC, Blurton-Jones M, Swarup V, Poon WW, Lim RG, Thompson LM. Reyes-Ortiz AM, et al. Among authors: miyoshi e. iScience. 2022 Dec 6;26(1):105732. doi: 10.1016/j.isci.2022.105732. eCollection 2023 Jan 20. iScience. 2022. PMID: 36590162 Free PMC article.
395 results