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Outcomes in ANCA-Associated Vasculitis in Scotland: Validation of the Renal Risk Score in a Complete National Cohort.
McGovern DP, Lees JS, Traynor JP, Mackinnon B, Bell S, Hunter RW, Dhaun N, Metcalfe W, Kidder D, Lim M, Joss N, Kelly M, Taylor A, Cousland Z, Dey V, Buck K, Brix S, Geddes CC, McQuarrie EP, Stevens KI. McGovern DP, et al. Kidney Int Rep. 2023 Jun 2;8(8):1648-1656. doi: 10.1016/j.ekir.2023.05.029. eCollection 2023 Aug. Kidney Int Rep. 2023. PMID: 37547534 Free PMC article.
Long-term outcomes in elderly patients with ANCA-associated vasculitis.
McGovern D, Williams SP, Parsons K, Farrah TE, Gallacher PJ, Miller-Hodges E, Kluth DC, Hunter RW, Dhaun N. McGovern D, et al. Rheumatology (Oxford). 2020 May 1;59(5):1076-1083. doi: 10.1093/rheumatology/kez388. Rheumatology (Oxford). 2020. PMID: 31794032 Free PMC article.
The Improved Kidney Risk Score in ANCA-Associated Vasculitis for Clinical Practice and Trials.
Bate S, McGovern D, Costigliolo F, Tan PG, Kratky V, Scott J, Chapman GB, Brown N, Floyd L, Brilland B, Martín-Nares E, Aydın MF, Ilyas D, Butt A, Nic An Riogh E, Kollar M, Lees JS, Yildiz A, Hinojosa-Azaola A, Dhaygude A, Roberts SA, Rosenberg A, Wiech T, Pusey CD, Jones RB, Jayne DRW, Bajema I, Jennette JC, Stevens KI, Augusto JF, Mejía-Vilet JM, Dhaun N, McAdoo SP, Tesar V, Little MA, Geetha D, Brix SR. Bate S, et al. J Am Soc Nephrol. 2024 Mar 1;35(3):335-346. doi: 10.1681/ASN.0000000000000274. Epub 2023 Dec 12. J Am Soc Nephrol. 2024. PMID: 38082490
Macrophage LRRK2 hyperactivity impairs autophagy and induces Paneth cell dysfunction.
Sun S, Hodel M, Wang X, De Vicente J, Haritunians T, Debebe A, Hung CT, Ma C, Malique A, Nguyen HN, Agam M, Maloney MT, Goo MS, Kluss JH, Mishra R, Frein J, Foster A, Ballentine S, Pandey U, Kern J, Yang S, Mengesha E, Balasubramanian I, Arguello A, Estrada AA, Gao N, Peter I, McGovern DPB, Henry AG, Stappenbeck TS, Liu TC. Sun S, et al. Among authors: mcgovern dpb. Sci Immunol. 2024 Nov 8;9(101):eadi7907. doi: 10.1126/sciimmunol.adi7907. Epub 2024 Nov 8. Sci Immunol. 2024. PMID: 39514635
A Proteomics Pipeline for Generating Clinical Grade Biomarker Candidates from Data-Independent Acquisition Mass Spectrometry (DIA-MS) Discovery.
Fu Q, Vegesna M, Sundararaman N, Damoc E, Arrey TN, Pashkova A, Mengesha E, Debbas P, Joung S, Li D, Cheng S, Braun J, McGovern DPB, Murray CI, Xuan Y, Van Eyk JE. Fu Q, et al. Among authors: mcgovern dpb. Angew Chem Int Ed Engl. 2024 Dec 20;63(52):e202409446. doi: 10.1002/anie.202409446. Epub 2024 Nov 11. Angew Chem Int Ed Engl. 2024. PMID: 39432331
The JAK inhibitor, Tofacitinib, Corrects the Overexpression of CEACAM6 and Limits Susceptibility to AIEC Caused by Reduced Activity of the IBD Associated Gene, PTPN2.
Chatterjee P, Canale V, King SJ, Shawki A, Lei H, Haddad M, Gries CM, McGovern DPB, Borneman J, McCole DF. Chatterjee P, et al. Among authors: mcgovern dpb. medRxiv [Preprint]. 2024 Sep 28:2024.09.26.24314341. doi: 10.1101/2024.09.26.24314341. medRxiv. 2024. PMID: 39399045 Free PMC article. Preprint.
Phase 2 Trial of Anti-TL1A Monoclonal Antibody Tulisokibart for Ulcerative Colitis.
Sands BE, Feagan BG, Peyrin-Biroulet L, Danese S, Rubin DT, Laurent O, Luo A, Nguyen DD, Lu J, Yen M, Leszczyszyn J, Kempiński R, McGovern DPB, Ma C, Ritter TE, Targan S; ARTEMIS-UC Study Group. Sands BE, et al. Among authors: mcgovern dpb. N Engl J Med. 2024 Sep 26;391(12):1119-1129. doi: 10.1056/NEJMoa2314076. N Engl J Med. 2024. PMID: 39321363 Clinical Trial.
276 results