Huang TT - Search Results

1

Transcription-Replication Conflicts as a Source of Genome Instability.

Goehring L, Huang TT, Smith DJ. Goehring L, et al. Among authors: huang tt. Annu Rev Genet. 2023 Nov 27;57:157-179. doi: 10.1146/annurev-genet-080320-031523. Epub 2023 Aug 8. Annu Rev Genet. 2023. PMID: 37552891 Free PMC article. Review.

2

Transcription shapes DNA replication initiation and termination in human cells.

Chen YH, Keegan S, Kahli M, Tonzi P, Fenyö D, Huang TT, Smith DJ. Chen YH, et al. Among authors: huang tt. Nat Struct Mol Biol. 2019 Jan;26(1):67-77. doi: 10.1038/s41594-018-0171-0. Epub 2018 Dec 31. Nat Struct Mol Biol. 2019. PMID: 30598550 Free PMC article.

3

Monitoring genome-wide replication fork directionality by Okazaki fragment sequencing in mammalian cells.

Kit Leng Lui S, Keegan S, Tonzi P, Kahli M, Chen YH, Chalhoub N, Coleman KE, Fenyo D, Smith DJ, Huang TT. Kit Leng Lui S, et al. Among authors: huang tt. Nat Protoc. 2021 Feb;16(2):1193-1218. doi: 10.1038/s41596-020-00454-5. Epub 2021 Jan 13. Nat Protoc. 2021. PMID: 33442052 Free PMC article.

4

WEE1i-ATRi combination therapy: a promising low-dose treatment for CCNE1-amplified gynecologic cancers.

Goehring L, Huang TT. Goehring L, et al. Among authors: huang tt. Cell Rep Med. 2021 Sep 23;2(9):100402. doi: 10.1016/j.xcrm.2021.100402. eCollection 2021 Sep 21. Cell Rep Med. 2021. PMID: 34622238 Free PMC article.

5

USP1-trapping lesions as a source of DNA replication stress and genomic instability.

Coleman KE, Yin Y, Lui SKL, Keegan S, Fenyo D, Smith DJ, Rothenberg E, Huang TT. Coleman KE, et al. Among authors: huang tt. Nat Commun. 2022 Apr 1;13(1):1740. doi: 10.1038/s41467-022-29369-3. Nat Commun. 2022. PMID: 35365626 Free PMC article.

6

Dormant origin firing promotes head-on transcription-replication conflicts at transcription termination sites in response to BRCA2 deficiency.

Goehring L, Keegan S, Lahiri S, Xia W, Kong M, Jimenez-Sainz J, Gupta D, Drapkin R, Jensen RB, Smith DJ, Rothenberg E, Fenyö D, Huang TT. Goehring L, et al. Among authors: huang tt. Nat Commun. 2024 Jun 3;15(1):4716. doi: 10.1038/s41467-024-48286-1. Nat Commun. 2024. PMID: 38830843 Free PMC article.

7

Transcription-replication conflicts as a source of common fragile site instability caused by BMI1-RNF2 deficiency.

Sanchez A, de Vivo A, Tonzi P, Kim J, Huang TT, Kee Y. Sanchez A, et al. Among authors: huang tt. PLoS Genet. 2020 Mar 6;16(3):e1008524. doi: 10.1371/journal.pgen.1008524. eCollection 2020 Mar. PLoS Genet. 2020. PMID: 32142505 Free PMC article.

8

Dysregulation of DNA polymerase κ recruitment to replication forks results in genomic instability.

Jones MJ, Colnaghi L, Huang TT. Jones MJ, et al. Among authors: huang tt. EMBO J. 2012 Feb 15;31(4):908-18. doi: 10.1038/emboj.2011.457. Epub 2011 Dec 13. EMBO J. 2012. PMID: 22157819 Free PMC article.

9

How SUMOylation Fine-Tunes the Fanconi Anemia DNA Repair Pathway.

Coleman KE, Huang TT. Coleman KE, et al. Among authors: huang tt. Front Genet. 2016 Apr 19;7:61. doi: 10.3389/fgene.2016.00061. eCollection 2016. Front Genet. 2016. PMID: 27148358 Free PMC article. Review.

10

Role of Deubiquitinating Enzymes in DNA Repair.

Kee Y, Huang TT. Kee Y, et al. Among authors: huang tt. Mol Cell Biol. 2015 Dec 7;36(4):524-44. doi: 10.1128/MCB.00847-15. Print 2016 Feb 15. Mol Cell Biol. 2015. PMID: 26644404 Free PMC article. Review.

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