Smith DJ - Search Results

1

Transcription-Replication Conflicts as a Source of Genome Instability.

Goehring L, Huang TT, Smith DJ. Goehring L, et al. Among authors: smith dj. Annu Rev Genet. 2023 Nov 27;57:157-179. doi: 10.1146/annurev-genet-080320-031523. Epub 2023 Aug 8. Annu Rev Genet. 2023. PMID: 37552891 Free PMC article. Review.

2

Transcription shapes DNA replication initiation and termination in human cells.

Chen YH, Keegan S, Kahli M, Tonzi P, Fenyö D, Huang TT, Smith DJ. Chen YH, et al. Among authors: smith dj. Nat Struct Mol Biol. 2019 Jan;26(1):67-77. doi: 10.1038/s41594-018-0171-0. Epub 2018 Dec 31. Nat Struct Mol Biol. 2019. PMID: 30598550 Free PMC article.

3

Monitoring genome-wide replication fork directionality by Okazaki fragment sequencing in mammalian cells.

Kit Leng Lui S, Keegan S, Tonzi P, Kahli M, Chen YH, Chalhoub N, Coleman KE, Fenyo D, Smith DJ, Huang TT. Kit Leng Lui S, et al. Among authors: smith dj. Nat Protoc. 2021 Feb;16(2):1193-1218. doi: 10.1038/s41596-020-00454-5. Epub 2021 Jan 13. Nat Protoc. 2021. PMID: 33442052 Free PMC article.

4

USP1-trapping lesions as a source of DNA replication stress and genomic instability.

Coleman KE, Yin Y, Lui SKL, Keegan S, Fenyo D, Smith DJ, Rothenberg E, Huang TT. Coleman KE, et al. Among authors: smith dj. Nat Commun. 2022 Apr 1;13(1):1740. doi: 10.1038/s41467-022-29369-3. Nat Commun. 2022. PMID: 35365626 Free PMC article.

5

Dormant origin firing promotes head-on transcription-replication conflicts at transcription termination sites in response to BRCA2 deficiency.

Goehring L, Keegan S, Lahiri S, Xia W, Kong M, Jimenez-Sainz J, Gupta D, Drapkin R, Jensen RB, Smith DJ, Rothenberg E, Fenyö D, Huang TT. Goehring L, et al. Among authors: smith dj. Nat Commun. 2024 Jun 3;15(1):4716. doi: 10.1038/s41467-024-48286-1. Nat Commun. 2024. PMID: 38830843 Free PMC article.

6

Determinants of Replication-Fork Pausing at tRNA Genes in Saccharomyces cerevisiae.

Yeung R, Smith DJ. Yeung R, et al. Among authors: smith dj. Genetics. 2020 Apr;214(4):825-838. doi: 10.1534/genetics.120.303092. Epub 2020 Feb 18. Genetics. 2020. PMID: 32071194 Free PMC article.

7

Quantitative, genome-wide analysis of eukaryotic replication initiation and termination.

McGuffee SR, Smith DJ, Whitehouse I. McGuffee SR, et al. Among authors: smith dj. Mol Cell. 2013 Apr 11;50(1):123-35. doi: 10.1016/j.molcel.2013.03.004. Epub 2013 Apr 4. Mol Cell. 2013. PMID: 23562327 Free PMC article.

8

Pif1-family helicases cooperatively suppress widespread replication-fork arrest at tRNA genes.

Osmundson JS, Kumar J, Yeung R, Smith DJ. Osmundson JS, et al. Among authors: smith dj. Nat Struct Mol Biol. 2017 Feb;24(2):162-170. doi: 10.1038/nsmb.3342. Epub 2016 Dec 19. Nat Struct Mol Biol. 2017. PMID: 27991904 Free PMC article.

9

Evidence of RNA polymerase III recruitment and transcription at protein-coding gene promoters.

K C R, Cheng R, Zhou S, Lizarazo S, Smith DJ, Van Bortle K. K C R, et al. Among authors: smith dj. Mol Cell. 2024 Nov 7;84(21):4111-4124.e5. doi: 10.1016/j.molcel.2024.09.019. Epub 2024 Oct 10. Mol Cell. 2024. PMID: 39393362

10

Chromatin dynamics at the replication fork: there's more to life than histones.

Whitehouse I, Smith DJ. Whitehouse I, et al. Among authors: smith dj. Curr Opin Genet Dev. 2013 Apr;23(2):140-6. doi: 10.1016/j.gde.2012.12.007. Epub 2013 Jan 21. Curr Opin Genet Dev. 2013. PMID: 23347596 Free PMC article. Review.

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