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A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants.
Pérez-Vargas J, Worrall LJ, Olmstead AD, Ton AT, Lee J, Villanueva I, Thompson CAH, Dudek S, Ennis S, Smith JR, Shapira T, De Guzman J, Gang S, Ban F, Vuckovic M, Bielecki M, Kovacic S, Kenward C, Hong CY, Gordon DG, Levett PN, Krajden M, Leduc R, Boudreault PL, Niikura M, Paetzel M, Young RN, Cherkasov A, Strynadka NCJ, Jean F. Pérez-Vargas J, et al. Among authors: krajden m. Emerg Microbes Infect. 2023 Dec;12(2):2246594. doi: 10.1080/22221751.2023.2246594. Emerg Microbes Infect. 2023. PMID: 37555275 Free PMC article.
Methamphetamine injecting is associated with phylogenetic clustering of hepatitis C virus infection among street-involved youth in Vancouver, Canada.
Cunningham EB, Jacka B, DeBeck K, Applegate TL, Harrigan PR, Krajden M, Marshall BD, Montaner J, Lima VD, Olmstead AD, Milloy MJ, Wood E, Grebely J. Cunningham EB, et al. Among authors: krajden m. Drug Alcohol Depend. 2015 Jul 1;152:272-6. doi: 10.1016/j.drugalcdep.2015.04.005. Epub 2015 Apr 20. Drug Alcohol Depend. 2015. PMID: 25977204 Free PMC article.
Treatment-Induced Viral Cure of Hepatitis C Virus-Infected Patients Involves a Dynamic Interplay among three Important Molecular Players in Lipid Homeostasis: Circulating microRNA (miR)-24, miR-223, and Proprotein Convertase Subtilisin/Kexin Type 9.
Hyrina A, Olmstead AD, Steven P, Krajden M, Tam E, Jean F. Hyrina A, et al. Among authors: krajden m. EBioMedicine. 2017 Sep;23:68-78. doi: 10.1016/j.ebiom.2017.08.020. Epub 2017 Aug 24. EBioMedicine. 2017. PMID: 28864162 Free PMC article.
Comparative Analysis of Capillary vs Venous Blood for Serologic Detection of SARS-CoV-2 Antibodies by RPOC Lateral Flow Tests.
Morshed M, Sekirov I, McLennan M, Levett PN, Chahil N, Mak A, Carruthers E, Pidduck T, Kustra J, Laley J, Lee MK, Chu K, Burgess F, Vijh R, Willis L, Wada R, Blancaflor R, Boraston S, Hayden A, Krajden M. Morshed M, et al. Among authors: krajden m. Open Forum Infect Dis. 2021 Jan 28;8(3):ofab043. doi: 10.1093/ofid/ofab043. eCollection 2021 Mar. Open Forum Infect Dis. 2021. PMID: 33723509 Free PMC article.
SARS-CoV-2 serology: Validation of high-throughput chemiluminescent immunoassay (CLIA) platforms and a field study in British Columbia.
Sekirov I, Barakauskas VE, Simons J, Cook D, Bates B, Burns L, Masud S, Charles M, McLennan M, Mak A, Chahil N, Vijh R, Hayden A, Goldfarb D, Levett PN, Krajden M, Morshed M. Sekirov I, et al. Among authors: krajden m. J Clin Virol. 2021 Sep;142:104914. doi: 10.1016/j.jcv.2021.104914. Epub 2021 Jul 16. J Clin Virol. 2021. PMID: 34304088 Free PMC article.
387 results