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SARS-CoV-2 vaccination, booster, and infection in pregnant population enhances passive immunity in neonates.
Murphy EA, Guzman-Cardozo C, Sukhu AC, Parks DJ, Prabhu M, Mohammed I, Jurkiewicz M, Ketas TJ, Singh S, Canis M, Bednarski E, Hollingsworth A, Thompson EM, Eng D, Bieniasz PD, Riley LE, Hatziioannou T, Yang YJ. Murphy EA, et al. Among authors: parks dj. Nat Commun. 2023 Aug 10;14(1):4598. doi: 10.1038/s41467-023-39989-y. Nat Commun. 2023. PMID: 37563124 Free PMC article.
Discovery of novel potent imidazo[1,2-b]pyridazine PDE10a inhibitors.
Meegalla SK, Huang H, Illig CR, Parks DJ, Chen J, Lee YK, Wilson KJ, Patel SK, Cheung WS, Lu T, Kirchner T, Askari HB, Geisler J, Patch RJ, Gibbs AC, Rady B, Connelly M, Player MR. Meegalla SK, et al. Among authors: parks dj. Bioorg Med Chem Lett. 2016 Sep 1;26(17):4216-22. doi: 10.1016/j.bmcl.2016.07.054. Epub 2016 Jul 25. Bioorg Med Chem Lett. 2016. PMID: 27491708
Novel heterocyclic scaffolds of GW4064 as farnesoid X receptor agonists.
Smalley TL Jr, Boggs S, Caravella JA, Chen L, Creech KL, Deaton DN, Kaldor I, Parks DJ. Smalley TL Jr, et al. Among authors: parks dj. Bioorg Med Chem Lett. 2015 Jan 15;25(2):280-4. doi: 10.1016/j.bmcl.2014.11.050. Epub 2014 Nov 26. Bioorg Med Chem Lett. 2015. PMID: 25499883
Imidazo[1,2-a]pyridines That Directly Interact with Hepatitis C NS4B: Initial Preclinical Characterization.
Shotwell JB, Baskaran S, Chong P, Creech KL, Crosby RM, Dickson H, Fang J, Garrido D, Mathis A, Maung J, Parks DJ, Pouliot JJ, Price DJ, Rai R, Seal JW 3rd, Schmitz U, Tai VW, Thomson M, Xie M, Xiong ZZ, Peat AJ. Shotwell JB, et al. Among authors: parks dj. ACS Med Chem Lett. 2012 May 24;3(7):565-9. doi: 10.1021/ml300090x. eCollection 2012 Jul 12. ACS Med Chem Lett. 2012. PMID: 24900511 Free PMC article.
Conformationally constrained farnesoid X receptor (FXR) agonists: alternative replacements of the stilbene.
Akwabi-Ameyaw A, Caravella JA, Chen L, Creech KL, Deaton DN, Madauss KP, Marr HB, Miller AB, Navas F 3rd, Parks DJ, Spearing PK, Todd D, Williams SP, Wisely GB. Akwabi-Ameyaw A, et al. Among authors: parks dj. Bioorg Med Chem Lett. 2011 Oct 15;21(20):6154-60. doi: 10.1016/j.bmcl.2011.08.034. Epub 2011 Aug 11. Bioorg Med Chem Lett. 2011. PMID: 21890356
Conformationally constrained farnesoid X receptor (FXR) agonists: heteroaryl replacements of the naphthalene.
Bass JY, Caravella JA, Chen L, Creech KL, Deaton DN, Madauss KP, Marr HB, McFadyen RB, Miller AB, Mills WY, Navas F 3rd, Parks DJ, Smalley TL Jr, Spearing PK, Todd D, Williams SP, Wisely GB. Bass JY, et al. Among authors: parks dj. Bioorg Med Chem Lett. 2011 Feb 15;21(4):1206-13. doi: 10.1016/j.bmcl.2010.12.089. Epub 2010 Dec 23. Bioorg Med Chem Lett. 2011. PMID: 21256005
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