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Page 1
Hierarchical design of pseudosymmetric protein nanocages.
Dowling QM, Park YJ, Fries CN, Gerstenmaier NC, Ols S, Yang EC, Wargacki AJ, Dosey A, Hsia Y, Ravichandran R, Walkey CD, Burrell AL, Veesler D, Baker D, King NP. Dowling QM, et al. Nature. 2024 Dec 18. doi: 10.1038/s41586-024-08360-6. Online ahead of print. Nature. 2024. PMID: 39695230
Rapid and automated design of two-component protein nanomaterials using ProteinMPNN.
de Haas RJ, Brunette N, Goodson A, Dauparas J, Yi SY, Yang EC, Dowling Q, Nguyen H, Kang A, Bera AK, Sankaran B, de Vries R, Baker D, King NP. de Haas RJ, et al. Among authors: dowling q. Proc Natl Acad Sci U S A. 2024 Mar 26;121(13):e2314646121. doi: 10.1073/pnas.2314646121. Epub 2024 Mar 19. Proc Natl Acad Sci U S A. 2024. PMID: 38502697 Free PMC article.
Accurate computational design of three-dimensional protein crystals.
Li Z, Wang S, Nattermann U, Bera AK, Borst AJ, Yaman MY, Bick MJ, Yang EC, Sheffler W, Lee B, Seifert S, Hura GL, Nguyen H, Kang A, Dalal R, Lubner JM, Hsia Y, Haddox H, Courbet A, Dowling Q, Miranda M, Favor A, Etemadi A, Edman NI, Yang W, Weidle C, Sankaran B, Negahdari B, Ross MB, Ginger DS, Baker D. Li Z, et al. Among authors: dowling q. Nat Mater. 2023 Dec;22(12):1556-1563. doi: 10.1038/s41563-023-01683-1. Epub 2023 Oct 16. Nat Mater. 2023. PMID: 37845322 Free article.
Rapid and automated design of two-component protein nanomaterials using ProteinMPNN.
de Haas RJ, Brunette N, Goodson A, Dauparas J, Yi SY, Yang EC, Dowling Q, Nguyen H, Kang A, Bera AK, Sankaran B, de Vries R, Baker D, King NP. de Haas RJ, et al. Among authors: dowling q. bioRxiv [Preprint]. 2023 Aug 4:2023.08.04.551935. doi: 10.1101/2023.08.04.551935. bioRxiv. 2023. Update in: Proc Natl Acad Sci U S A. 2024 Mar 26;121(13):e2314646121. doi: 10.1073/pnas.2314646121 PMID: 37577478 Free PMC article. Updated. Preprint.
Fast and versatile sequence-independent protein docking for nanomaterials design using RPXDock.
Sheffler W, Yang EC, Dowling Q, Hsia Y, Fries CN, Stanislaw J, Langowski MD, Brandys M, Li Z, Skotheim R, Borst AJ, Khmelinskaia A, King NP, Baker D. Sheffler W, et al. Among authors: dowling q. PLoS Comput Biol. 2023 May 22;19(5):e1010680. doi: 10.1371/journal.pcbi.1010680. eCollection 2023 May. PLoS Comput Biol. 2023. PMID: 37216343 Free PMC article.
Computational design of constitutively active cGAS.
Dowling QM, Volkman HE, Gray EE, Ovchinnikov S, Cambier S, Bera AK, Sankaran B, Johnson MR, Bick MJ, Kang A, Stetson DB, King NP. Dowling QM, et al. Nat Struct Mol Biol. 2023 Jan;30(1):72-80. doi: 10.1038/s41594-022-00862-z. Epub 2023 Jan 2. Nat Struct Mol Biol. 2023. PMID: 36593311
De novo design of self-assembling helical protein filaments.
Shen H, Fallas JA, Lynch E, Sheffler W, Parry B, Jannetty N, Decarreau J, Wagenbach M, Vicente JJ, Chen J, Wang L, Dowling Q, Oberdorfer G, Stewart L, Wordeman L, De Yoreo J, Jacobs-Wagner C, Kollman J, Baker D. Shen H, et al. Among authors: dowling q. Science. 2018 Nov 9;362(6415):705-709. doi: 10.1126/science.aau3775. Science. 2018. PMID: 30409885 Free PMC article.
19 results