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Page 1
Trisomy of human chromosome 21 enhances amyloid-β deposition independently of an extra copy of APP.
Wiseman FK, Pulford LJ, Barkus C, Liao F, Portelius E, Webb R, Chávez-Gutiérrez L, Cleverley K, Noy S, Sheppard O, Collins T, Powell C, Sarell CJ, Rickman M, Choong X, Tosh JL, Siganporia C, Whittaker HT, Stewart F, Szaruga M; London Down syndrome consortium; Murphy MP, Blennow K, de Strooper B, Zetterberg H, Bannerman D, Holtzman DM, Tybulewicz VLJ, Fisher EMC; LonDownS Consortium. Wiseman FK, et al. Among authors: fisher emc. Brain. 2018 Aug 1;141(8):2457-2474. doi: 10.1093/brain/awy159. Brain. 2018. PMID: 29945247 Free PMC article.
Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain.
Alić I, Goh PA, Murray A, Portelius E, Gkanatsiou E, Gough G, Mok KY, Koschut D, Brunmeir R, Yeap YJ, O'Brien NL, Groet J, Shao X, Havlicek S, Dunn NR, Kvartsberg H, Brinkmalm G, Hithersay R, Startin C, Hamburg S, Phillips M, Pervushin K, Turmaine M, Wallon D, Rovelet-Lecrux A, Soininen H, Volpi E, Martin JE, Foo JN, Becker DL, Rostagno A, Ghiso J, Krsnik Ž, Šimić G, Kostović I, Mitrečić D; LonDownS Consortium; Francis PT, Blennow K, Strydom A, Hardy J, Zetterberg H, Nižetić D. Alić I, et al. Mol Psychiatry. 2021 Oct;26(10):5766-5788. doi: 10.1038/s41380-020-0806-5. Epub 2020 Jul 10. Mol Psychiatry. 2021. PMID: 32647257 Free PMC article.
Publisher Correction: Genetic dissection of down syndrome‑associated alterations in APP/amyloid‑β biology using mouse models.
Tosh JL, Rhymes ER, Mumford P, Whittaker HT, Pulford LJ, Noy SJ, Cleverley K; LonDownS Consortium; Walker MC, Tybulewicz VLJ, Wykes RC, Fisher EMC, Wiseman FK. Tosh JL, et al. Among authors: fisher emc. Sci Rep. 2021 Jul 16;11(1):14966. doi: 10.1038/s41598-021-94313-2. Sci Rep. 2021. PMID: 34272456 Free PMC article. No abstract available.
Affordable optical clearing and immunolabelling in mouse brain slices.
Muza PM, Pérez M, Noy S, Kurosawa M, Katsouri L, Tybulewicz VLJ, Fisher EMC, West SJ. Muza PM, et al. Among authors: fisher emc. BMC Res Notes. 2023 Sep 30;16(1):246. doi: 10.1186/s13104-023-06511-y. BMC Res Notes. 2023. PMID: 37777793 Free PMC article.
182 results