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Canonical and noncanonical Wnt signaling: Multilayered mediators, signaling mechanisms and major signaling crosstalk.
Qin K, Yu M, Fan J, Wang H, Zhao P, Zhao G, Zeng W, Chen C, Wang Y, Wang A, Schwartz Z, Hong J, Song L, Wagstaff W, Haydon RC, Luu HH, Ho SH, Strelzow J, Reid RR, He TC, Shi LL. Qin K, et al. Among authors: chen c. Genes Dis. 2023 Mar 24;11(1):103-134. doi: 10.1016/j.gendis.2023.01.030. eCollection 2024 Jan. Genes Dis. 2023. PMID: 37588235 Free PMC article. Review.
Blockade of IGF/IGF-1R signaling axis with soluble IGF-1R mutants suppresses the cell proliferation and tumor growth of human osteosarcoma.
Cao D, Lei Y, Ye Z, Zhao L, Wang H, Zhang J, He F, Huang L, Shi D, Liu Q, Ni N, Pakvasa M, Wagstaff W, Zhao X, Fu K, Tucker AB, Chen C, Reid RR, Haydon RC, Luu HH, He TC, Liao Z. Cao D, et al. Among authors: chen c. Am J Cancer Res. 2020 Oct 1;10(10):3248-3266. eCollection 2020. Am J Cancer Res. 2020. PMID: 33163268 Free PMC article.
Stem Cell-Friendly Scaffold Biomaterials: Applications for Bone Tissue Engineering and Regenerative Medicine.
Zhang Y, Wu D, Zhao X, Pakvasa M, Tucker AB, Luo H, Qin KH, Hu DA, Wang EJ, Li AJ, Zhang M, Mao Y, Sabharwal M, He F, Niu C, Wang H, Huang L, Shi D, Liu Q, Ni N, Fu K, Chen C, Wagstaff W, Reid RR, Athiviraham A, Ho S, Lee MJ, Hynes K, Strelzow J, He TC, El Dafrawy M. Zhang Y, et al. Among authors: chen c. Front Bioeng Biotechnol. 2020 Dec 14;8:598607. doi: 10.3389/fbioe.2020.598607. eCollection 2020. Front Bioeng Biotechnol. 2020. PMID: 33381499 Free PMC article. Review.
The inhibition of BRAF activity sensitizes chemoresistant human ovarian cancer cells to paclitaxel-induced cytotoxicity and tumor growth inhibition.
Zhao L, Huang L, Zhang J, Fan J, He F, Zhao X, Wang H, Liu Q, Shi D, Ni N, Wagstaff W, Pakvasa M, Fu K, Tucker AB, Chen C, Reid RR, Haydon RC, Luu HH, Shen L, Qi H, He TC. Zhao L, et al. Among authors: chen c. Am J Transl Res. 2020 Dec 15;12(12):8084-8098. eCollection 2020. Am J Transl Res. 2020. PMID: 33437383 Free PMC article.
A functional autophagy pathway is essential for BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs).
Zhao X, Huang B, Wang H, Ni N, He F, Liu Q, Shi D, Chen C, Zhao P, Wang X, Wagstaff W, Pakvasa M, Tucker AB, Lee MJ, Wolf JM, Reid RR, Hynes K, Strelzow J, Ho SH, Yu T, Yang J, Shen L, He TC, Zhang Y. Zhao X, et al. Among authors: chen c. Am J Transl Res. 2021 May 15;13(5):4233-4250. eCollection 2021. Am J Transl Res. 2021. PMID: 34150011 Free PMC article.
Antiparasitic mebendazole (MBZ) effectively overcomes cisplatin resistance in human ovarian cancer cells by inhibiting multiple cancer-associated signaling pathways.
Huang L, Zhao L, Zhang J, He F, Wang H, Liu Q, Shi D, Ni N, Wagstaff W, Chen C, Reid RR, Haydon RC, Luu HH, Shen L, He TC, Tang L. Huang L, et al. Among authors: chen c. Aging (Albany NY). 2021 Jul 7;13(13):17407-17427. doi: 10.18632/aging.203232. Epub 2021 Jul 7. Aging (Albany NY). 2021. PMID: 34232919 Free PMC article.
Argonaute (AGO) proteins play an essential role in mediating BMP9-induced osteogenic signaling in mesenchymal stem cells (MSCs).
Mao Y, Ni N, Huang L, Fan J, Wang H, He F, Liu Q, Shi D, Fu K, Pakvasa M, Wagstaff W, Tucker AB, Chen C, Reid RR, Haydon RC, Ho SH, Lee MJ, He TC, Yang J, Shen L, Cai L, Luu HH. Mao Y, et al. Among authors: chen c. Genes Dis. 2021 May 13;8(6):918-930. doi: 10.1016/j.gendis.2021.04.004. eCollection 2021 Nov. Genes Dis. 2021. PMID: 34522718 Free PMC article.
Reversibly immortalized keratinocytes (iKera) facilitate re-epithelization and skin wound healing: Potential applications in cell-based skin tissue engineering.
Zhong J, Wang H, Yang K, Wang H, Duan C, Ni N, An L, Luo Y, Zhao P, Gou Y, Sheng S, Shi D, Chen C, Wagstaff W, Hendren-Santiago B, Haydon RC, Luu HH, Reid RR, Ho SH, Ameer GA, Shen L, He TC, Fan J. Zhong J, et al. Among authors: chen c. Bioact Mater. 2021 Jul 29;9:523-540. doi: 10.1016/j.bioactmat.2021.07.022. eCollection 2022 Mar. Bioact Mater. 2021. PMID: 34820586 Free PMC article.
OUHP: an optimized universal hairpin primer system for cost-effective and high-throughput RT-qPCR-based quantification of microRNA (miRNA) expression.
He F, Ni N, Wang H, Zeng Z, Zhao P, Shi D, Xia Y, Chen C, Hu DA, Qin KH, Wagstaff W, Qin D, Hendren-Santiago B, Ho SH, Haydon RC, Luu HH, Reid RR, Shen L, Gan H, Fan J, He TC. He F, et al. Among authors: chen c. Nucleic Acids Res. 2022 Feb 28;50(4):e22. doi: 10.1093/nar/gkab1153. Nucleic Acids Res. 2022. PMID: 34850128 Free PMC article.
A one-step construction of adenovirus (OSCA) system using the Gibson DNA Assembly technology.
Ni N, Deng F, He F, Wang H, Shi D, Liao J, Zou Y, Wang H, Zhao P, Hu X, Chen C, Hu DA, Sabharwal M, Qin KH, Wagstaff W, Qin D, Hendren-Santiago B, Haydon RC, Luu HH, Reid RR, Shen L, He TC, Fan J. Ni N, et al. Among authors: chen c. Mol Ther Oncolytics. 2021 Nov 20;23:602-611. doi: 10.1016/j.omto.2021.11.011. eCollection 2021 Dec 17. Mol Ther Oncolytics. 2021. PMID: 34977337 Free PMC article.
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