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Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge.
Karasmanis EP, Reimer JM, Kendrick AA, Nguyen KHV, Rodriguez JA, Truong JB, Lahiri I, Reck-Peterson SL, Leschziner AE. Karasmanis EP, et al. Among authors: truong jb. Nat Struct Mol Biol. 2023 Sep;30(9):1357-1364. doi: 10.1038/s41594-023-01069-6. Epub 2023 Aug 24. Nat Struct Mol Biol. 2023. PMID: 37620585 Free PMC article.