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Sustained CD28 costimulation is required for self-renewal and differentiation of TCF-1+ PD-1+ CD8 T cells.
Humblin E, Korpas I, Lu J, Filipescu D, van der Heide V, Goldstein S, Vaidya A, Soares-Schanoski A, Casati B, Selvan ME, Gümüş ZH, Wieland A, Corrado M, Cohen-Gould L, Bernstein E, Homann D, Chipuk J, Kamphorst AO. Humblin E, et al. Among authors: korpas i. Sci Immunol. 2023 Aug 4;8(86):eadg0878. doi: 10.1126/sciimmunol.adg0878. Epub 2023 Aug 25. Sci Immunol. 2023. PMID: 37624910 Free PMC article.
ICOS limits memory-like properties and function of exhausted PD-1 + CD8 T cells.
Humblin E, Korpas I, Prokhnevska N, Vaidya A, Lu J, van der Heide V, Filipescu D, Bobrowski T, Marks A, Park MD, Bernstein E, Brown BD, Lujambio A, Dominguez-Sola D, Rosenberg BR, Kamphorst AO. Humblin E, et al. Among authors: korpas i. bioRxiv [Preprint]. 2024 Sep 20:2024.09.16.611518. doi: 10.1101/2024.09.16.611518. bioRxiv. 2024. PMID: 39345453 Free PMC article. Preprint.