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KRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells.
Mahadevan KK, McAndrews KM, LeBleu VS, Yang S, Lyu H, Li B, Sockwell AM, Kirtley ML, Morse SJ, Moreno Diaz BA, Kim MP, Feng N, Lopez AM, Guerrero PA, Paradiso F, Sugimoto H, Arian KA, Ying H, Barekatain Y, Sthanam LK, Kelly PJ, Maitra A, Heffernan TP, Kalluri R. Mahadevan KK, et al. Among authors: kalluri r. Cancer Cell. 2023 Sep 11;41(9):1606-1620.e8. doi: 10.1016/j.ccell.2023.07.002. Epub 2023 Aug 24. Cancer Cell. 2023. PMID: 37625401 Free PMC article.
The role of extracellular vesicles in cancer.
Kalluri R, McAndrews KM. Kalluri R, et al. Cell. 2023 Apr 13;186(8):1610-1626. doi: 10.1016/j.cell.2023.03.010. Cell. 2023. PMID: 37059067 Free PMC article. Review.
Engineered exosomes targeting MYC reverse the proneural-mesenchymal transition and extend survival of glioblastoma.
Haltom AR, Hassen WE, Hensel J, Kim J, Sugimoto H, Li B, McAndrews KM, Conner MR, Kirtley ML, Luo X, Xie B, Volpert OV, Olalekan S, Maltsev N, Basu A, LeBleu VS, Kalluri R. Haltom AR, et al. Among authors: kalluri r. Extracell Vesicle. 2022 Dec;1:100014. doi: 10.1016/j.vesic.2022.100014. Epub 2022 Oct 27. Extracell Vesicle. 2022. PMID: 37503329 Free PMC article.
Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells.
Mahadevan KK, LeBleu VS, Ramirez EV, Chen Y, Li B, Sockwell AM, Gagea M, Sugimoto H, Sthanam LK, Tampe D, Zeisberg M, Ying H, Jain AK, DePinho RA, Maitra A, McAndrews KM, Kalluri R. Mahadevan KK, et al. Among authors: kalluri r. Dev Cell. 2023 Sep 11;58(17):1562-1577.e8. doi: 10.1016/j.devcel.2023.07.025. Epub 2023 Aug 24. Dev Cell. 2023. PMID: 37625403 Free PMC article.
Exosomes modified with anti-MEK1 siRNA lead to an effective silencing of triple negative breast cancer cells.
Ferreira D, Santos-Pereira C, Costa M, Afonso J, Yang S, Hensel J, McAndrews KM, Longatto-Filho A, Fernandes R, Melo JB, Baltazar F, Moreira JN, Kalluri R, Rodrigues LR. Ferreira D, et al. Among authors: kalluri r. Biomater Adv. 2023 Nov;154:213643. doi: 10.1016/j.bioadv.2023.213643. Epub 2023 Sep 28. Biomater Adv. 2023. PMID: 37778291 Free article.
Author Correction: Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression.
Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, Kalluri R, Iacobuzio-Donahue CA, Wood LD, Hebrok M, Hansen K, Moses HL, Weaver VM. Laklai H, et al. Among authors: kalluri r. Nat Med. 2024 Mar;30(3):908. doi: 10.1038/s41591-023-02694-w. Nat Med. 2024. PMID: 38017076 No abstract available.
392 results