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Investigation of the Host Kinome Response to Coronavirus Infection Reveals PI3K/mTOR Inhibitors as Betacoronavirus Antivirals.
Fritch EJ, Mordant AL, Gilbert TSK, Wells CI, Yang X, Barker NK, Madden EA, Dinnon KH 3rd, Hou YJ, Tse LV, Castillo IN, Sims AC, Moorman NJ, Lakshmanane P, Willson TM, Herring LE, Graves LM, Baric RS. Fritch EJ, et al. Among authors: herring le. J Proteome Res. 2023 Oct 6;22(10):3159-3177. doi: 10.1021/acs.jproteome.3c00182. Epub 2023 Aug 27. J Proteome Res. 2023. PMID: 37634194
O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3.
Li X, Gong W, Wang H, Li T, Attri KS, Lewis RE, Kalil AC, Bhinderwala F, Powers R, Yin G, Herring LE, Asara JM, Lei YL, Yang X, Rodriguez DA, Yang M, Green DR, Singh PK, Wen H. Li X, et al. Among authors: herring le. Immunity. 2019 Apr 16;50(4):1115. doi: 10.1016/j.immuni.2019.03.008. Immunity. 2019. PMID: 30995496 Free PMC article. No abstract available.
Positive Cooperativity in Substrate Binding by Human Thymidylate Synthase.
Bonin JP, Sapienza PJ, Wilkerson E, Goldfarb D, Wang L, Herring L, Chen X, Major MB, Lee AL. Bonin JP, et al. Biophys J. 2021 Sep 21;120(18):4137. doi: 10.1016/j.bpj.2021.08.023. Epub 2021 Aug 24. Biophys J. 2021. PMID: 34433070 Free PMC article. No abstract available.
Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma.
McNeill RS, Canoutas DA, Stuhlmiller TJ, Dhruv HD, Irvin DM, Bash RE, Angus SP, Herring LE, Simon JM, Skinner KR, Limas JC, Chen X, Schmid RS, Siegel MB, Van Swearingen AED, Hadler MJ, Sulman EP, Sarkaria JN, Anders CK, Graves LM, Berens ME, Johnson GL, Miller CR. McNeill RS, et al. Among authors: herring le. Neuro Oncol. 2017 Oct 19;19(11):1469-1480. doi: 10.1093/neuonc/nox044. Neuro Oncol. 2017. PMID: 28379424 Free PMC article.
BIRC6 mediates imatinib resistance independently of Mcl-1.
Okumu DO, East MP, Levine M, Herring LE, Zhang R, Gilbert TSK, Litchfield DW, Zhang Y, Graves LM. Okumu DO, et al. Among authors: herring le. PLoS One. 2017 May 16;12(5):e0177871. doi: 10.1371/journal.pone.0177871. eCollection 2017. PLoS One. 2017. PMID: 28520795 Free PMC article.
Chronic E-Cigarette Exposure Alters the Human Bronchial Epithelial Proteome.
Ghosh A, Coakley RC, Mascenik T, Rowell TR, Davis ES, Rogers K, Webster MJ, Dang H, Herring LE, Sassano MF, Livraghi-Butrico A, Van Buren SK, Graves LM, Herman MA, Randell SH, Alexis NE, Tarran R. Ghosh A, et al. Among authors: herring le. Am J Respir Crit Care Med. 2018 Jul 1;198(1):67-76. doi: 10.1164/rccm.201710-2033OC. Am J Respir Crit Care Med. 2018. PMID: 29481290 Free PMC article.
117 results