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Modeling of a Novel Patient-Based MYO5B Point Mutation Reveals Insights Into MVID Pathogenesis.
Burman A, Momoh M, Sampson L, Skelton J, Roland JT, Ramos C, Krystofiak E, Acra S, Goldenring JR, Kaji I. Burman A, et al. Among authors: kaji i. Cell Mol Gastroenterol Hepatol. 2023;15(4):1022-1026. doi: 10.1016/j.jcmgh.2022.12.015. Epub 2022 Dec 31. Cell Mol Gastroenterol Hepatol. 2023. PMID: 36592862 Free PMC article. No abstract available.
Therapy Development for Microvillus Inclusion Disease using Patient-derived Enteroids.
Kalashyan M, Raghunathan K, Oller H, Theres MB, Jimenez L, Roland JT, Kolobova E, Hagen SJ, Goldsmith JD, Shub MD, Goldenring JR, Kaji I, Thiagarajah JR. Kalashyan M, et al. Among authors: kaji i. bioRxiv [Preprint]. 2023 Jan 29:2023.01.28.526036. doi: 10.1101/2023.01.28.526036. bioRxiv. 2023. Update in: J Clin Invest. 2023 Oct 16;133(20):e169234. doi: 10.1172/JCI169234 PMID: 36747680 Free PMC article. Updated. Preprint.
Increased intestinal permeability and downregulation of absorptive ion transporters Nhe3, Dra, and Sglt1 contribute to diarrhea during Clostridioides difficile infection.
Peritore-Galve FC, Kaji I, Smith A, Walker LM, Shupe JA, Washington MK, Algood HMS, Dudeja PK, Goldenring JR, Lacy DB. Peritore-Galve FC, et al. Among authors: kaji i. Gut Microbes. 2023 Jan-Dec;15(1):2225841. doi: 10.1080/19490976.2023.2225841. Gut Microbes. 2023. PMID: 37350393 Free PMC article.
Myosin Vb Traffics P-Glycoprotein to the Apical Membrane of Intestinal Epithelial Cells.
Dooley SA, Kolobova E, Burman A, Kaji I, Digrazia JR, Stubler R, Goldstein A, Packirisamy C, Coutts AW, Saqui-Salces M, Gao N, Engevik MA, Shub MD, Goldenring JR, Engevik AC. Dooley SA, et al. Among authors: kaji i. Gastroenterology. 2025 Jan;168(1):84-98.e9. doi: 10.1053/j.gastro.2024.09.007. Epub 2024 Sep 18. Gastroenterology. 2025. PMID: 39299401
Alterations in cellular metabolic pathway and epithelial cell maturation induced by MYO5B defects are partially reversible by LPAR5 activation.
Momoh M, Rathan-Kumar S, Burman A, Brown ME, Adeniran F, Ramos C, Goldenring JR, Roland JT, Kaji I. Momoh M, et al. Among authors: kaji i. Am J Physiol Gastrointest Liver Physiol. 2024 Dec 1;327(6):G877-G899. doi: 10.1152/ajpgi.00091.2024. Epub 2024 Oct 15. Am J Physiol Gastrointest Liver Physiol. 2024. PMID: 39404772 Free article.
Altered cellular metabolic pathway and epithelial cell maturation induced by MYO5B defects are partially reversible by LPAR5 activation.
Momoh M, Rathan-Kumar S, Burman A, Brown ME, Adeniran F, Ramos C, Goldenring JR, Roland JT, Kaji I. Momoh M, et al. Among authors: kaji i. bioRxiv [Preprint]. 2024 Sep 8:2024.09.03.610579. doi: 10.1101/2024.09.03.610579. bioRxiv. 2024. Update in: Am J Physiol Gastrointest Liver Physiol. 2024 Dec 1;327(6):G877-G899. doi: 10.1152/ajpgi.00091.2024 PMID: 39282272 Free PMC article. Updated. Preprint.
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