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WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE.
Zhang X, Brody JA, Graff M, Highland HM, Chami N, Xu H, Wang Z, Ferrier K, Chittoor G, Josyula NS, Li X, Li Z, Allison MA, Becker DM, Bielak LF, Bis JC, Boorgula MP, Bowden DW, Broome JG, Buth EJ, Carlson CS, Chang KM, Chavan S, Chiu YF, Chuang LM, Conomos MP, DeMeo DL, Du M, Duggirala R, Eng C, Fohner AE, Freedman BI, Garrett ME, Guo X, Haiman C, Heavner BD, Hidalgo B, Hixson JE, Ho YL, Hobbs BD, Hu D, Hui Q, Hwu CM, Jackson RD, Jain D, Kalyani RR, Kardia SLR, Kelly TN, Lange EM, LeNoir M, Li C, Marchand LL, McDonald MN, McHugh CP, Morrison AC, Naseri T; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; O'Connell J, O'Donnell CJ, Palmer ND, Pankow JS, Perry JA, Peters U, Preuss MH, Rao DC, Regan EA, Reupena SM, Roden DM, Rodriguez-Santana J, Sitlani CM, Smith JA, Tiwari HK, Vasan RS, Wang Z, Weeks DE, Wessel J, Wiggins KL, Wilkens LR, Wilson PWF, Yanek LR, Yoneda ZT, Zhao W, Zöllner S, Arnett DK, Ashley-Koch AE, Barnes KC, Blangero J, Boerwinkle E, Burchard EG, Carson AP, Chasman DI, Chen YI, Curran JE, Fornage M, Gordeuk VR, He J, Heckbert SR, Hou L, Irvin MR, Kooperberg C, Minster RL, Mitchell BD, Nouraie M, Psaty BM, Raffield LM, Reiner AP, Rich SS, Rotter J… See abstract for full author list ➔ Zhang X, et al. Among authors: eng c. medRxiv [Preprint]. 2023 Aug 22:2023.08.21.23293271. doi: 10.1101/2023.08.21.23293271. medRxiv. 2023. PMID: 37662265 Free PMC article. Preprint.
Beta 2-adrenergic receptor polymorphisms: pharmacogenetic response to bronchodilator among African American asthmatics.
Tsai HJ, Shaikh N, Kho JY, Battle N, Naqvi M, Navarro D, Matallana H, Lilly CM, Eng CS, Kumar G, Thyne S, Watson HG, Meade K, LeNoir M, Choudhry S, Burchard EG; Study of African Americans, Asthma, Genes Environments (SAGE). Tsai HJ, et al. Hum Genet. 2006 Jun;119(5):547-57. doi: 10.1007/s00439-006-0169-2. Epub 2006 Apr 5. Hum Genet. 2006. PMID: 16596417
ORMDL3 gene is associated with asthma in three ethnically diverse populations.
Galanter J, Choudhry S, Eng C, Nazario S, Rodríguez-Santana JR, Casal J, Torres-Palacios A, Salas J, Chapela R, Watson HG, Meade K, LeNoir M, Rodríguez-Cintrón W, Avila PC, Burchard EG. Galanter J, et al. Among authors: eng c. Am J Respir Crit Care Med. 2008 Jun 1;177(11):1194-200. doi: 10.1164/rccm.200711-1644OC. Epub 2008 Feb 28. Am J Respir Crit Care Med. 2008. PMID: 18310477 Free PMC article.
Genetic ancestry modifies pharmacogenetic gene-gene interaction for asthma.
Corvol H, De Giacomo A, Eng C, Seibold M, Ziv E, Chapela R, Rodriguez-Santana JR, Rodriguez-Cintron W, Thyne S, Watson HG, Meade K, LeNoir M, Avila PC, Choudhry S, Burchard EG; Genetics of Asthma in Latino Americans (GALA) Study; Study of African-Americans, Asthma, Genes and Environments (SAGE) Investigators. Corvol H, et al. Among authors: eng c. Pharmacogenet Genomics. 2009 Jul;19(7):489-96. doi: 10.1097/FPC.0b013e32832c440e. Pharmacogenet Genomics. 2009. PMID: 19503017 Free PMC article.
Genome-wide association study implicates chromosome 9q21.31 as a susceptibility locus for asthma in mexican children.
Hancock DB, Romieu I, Shi M, Sienra-Monge JJ, Wu H, Chiu GY, Li H, del Rio-Navarro BE, Willis-Owen SA, Weiss ST, Raby BA, Gao H, Eng C, Chapela R, Burchard EG, Tang H, Sullivan PF, London SJ. Hancock DB, et al. Among authors: eng c. PLoS Genet. 2009 Aug;5(8):e1000623. doi: 10.1371/journal.pgen.1000623. Epub 2009 Aug 28. PLoS Genet. 2009. PMID: 19714205 Free PMC article.
A genome-wide association study on African-ancestry populations for asthma.
Mathias RA, Grant AV, Rafaels N, Hand T, Gao L, Vergara C, Tsai YJ, Yang M, Campbell M, Foster C, Gao P, Togias A, Hansel NN, Diette G, Adkinson NF, Liu MC, Faruque M, Dunston GM, Watson HR, Bracken MB, Hoh J, Maul P, Maul T, Jedlicka AE, Murray T, Hetmanski JB, Ashworth R, Ongaco CM, Hetrick KN, Doheny KF, Pugh EW, Rotimi CN, Ford J, Eng C, Burchard EG, Sleiman PM, Hakonarson H, Forno E, Raby BA, Weiss ST, Scott AF, Kabesch M, Liang L, Abecasis G, Moffatt MF, Cookson WO, Ruczinski I, Beaty TH, Barnes KC. Mathias RA, et al. Among authors: eng c. J Allergy Clin Immunol. 2010 Feb;125(2):336-346.e4. doi: 10.1016/j.jaci.2009.08.031. Epub 2009 Nov 11. J Allergy Clin Immunol. 2010. PMID: 19910028 Free PMC article.
Dual-specificity phosphatase 1 as a pharmacogenetic modifier of inhaled steroid response among asthmatic patients.
Jin Y, Hu D, Peterson EL, Eng C, Levin AM, Wells K, Beckman K, Kumar R, Seibold MA, Karungi G, Zoratti A, Gaggin J, Campbell J, Galanter J, Chapela R, Rodríguez-Santana JR, Watson HG, Meade K, Lenoir M, Rodríguez-Cintrón W, Avila PC, Lanfear DE, Burchard EG, Williams LK. Jin Y, et al. Among authors: eng c. J Allergy Clin Immunol. 2010 Sep;126(3):618-25.e1-2. doi: 10.1016/j.jaci.2010.06.007. Epub 2010 Jul 31. J Allergy Clin Immunol. 2010. PMID: 20673984 Free PMC article. Clinical Trial.
Cosmopolitan and ethnic-specific replication of genetic risk factors for asthma in 2 Latino populations.
Galanter JM, Torgerson D, Gignoux CR, Sen S, Roth LA, Via M, Aldrich MC, Eng C, Huntsman S, Rodriguez-Santana J, Rodriguez-Cintrón W, Chapela R, Ford JG, Burchard EG. Galanter JM, et al. Among authors: eng c. J Allergy Clin Immunol. 2011 Jul;128(1):37-43.e12. doi: 10.1016/j.jaci.2011.03.050. Epub 2011 May 28. J Allergy Clin Immunol. 2011. PMID: 21621256 Free PMC article.
1,912 results