Wu D - Search Results

1

Inhibition of AKR1Cs by liquiritigenin and the structural basis.

Liu H, Yao Z, Sun M, Zhang C, Huang YY, Luo HB, Wu D, Zheng X. Liu H, et al. Among authors: wu d. Chem Biol Interact. 2023 Nov 1;385:110654. doi: 10.1016/j.cbi.2023.110654. Epub 2023 Sep 2. Chem Biol Interact. 2023. PMID: 37666442

2

Palladium-catalyzed C-H bond carboxylation of acetanilides: an efficient usage of N,N-dimethyloxamic acid as the carboxylate source.

Wu Y, Jiang C, Wu D, Gu Q, Luo ZY, Luo HB. Wu Y, et al. Among authors: wu d. Chem Commun (Camb). 2016 Jan 21;52(6):1286-9. doi: 10.1039/c5cc07890c. Chem Commun (Camb). 2016. PMID: 26616015

3

3D-QSAR studies of 3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic acids as AKR1C3 inhibitors: Highlight the importance of molecular docking in conformation generation.

Zheng X, Wu Y, Wu D, Wang X, Zhang C, Guo X, Luo HB. Zheng X, et al. Among authors: wu y, wu d. Bioorg Med Chem Lett. 2016 Dec 1;26(23):5631-5638. doi: 10.1016/j.bmcl.2016.10.073. Epub 2016 Nov 1. Bioorg Med Chem Lett. 2016. PMID: 27847272

4

Discovery of Novel Phosphodiesterase-2A Inhibitors by Structure-Based Virtual Screening, Structural Optimization, and Bioassay.

Zhang C, Feng LJ, Huang Y, Wu D, Li Z, Zhou Q, Wu Y, Luo HB. Zhang C, et al. Among authors: wu y, wu d. J Chem Inf Model. 2017 Feb 27;57(2):355-364. doi: 10.1021/acs.jcim.6b00551. Epub 2017 Jan 18. J Chem Inf Model. 2017. PMID: 28055196

5

The discovery, complex crystal structure, and recognition mechanism of a novel natural PDE4 inhibitor from Selaginella pulvinata.

Huang Y, Liu X, Wu D, Tang G, Lai Z, Zheng X, Yin S, Luo HB. Huang Y, et al. Among authors: wu d. Biochem Pharmacol. 2017 Apr 15;130:51-59. doi: 10.1016/j.bcp.2017.01.016. Epub 2017 Jan 31. Biochem Pharmacol. 2017. PMID: 28159622

6

Discovery and Optimization of Chromeno[2,3-c]pyrrol-9(2H)-ones as Novel Selective and Orally Bioavailable Phosphodiesterase 5 Inhibitors for the Treatment of Pulmonary Arterial Hypertension.

Wu D, Zhang T, Chen Y, Huang Y, Geng H, Yu Y, Zhang C, Lai Z, Wu Y, Guo X, Chen J, Luo HB. Wu D, et al. Among authors: wu y. J Med Chem. 2017 Aug 10;60(15):6622-6637. doi: 10.1021/acs.jmedchem.7b00523. Epub 2017 Jul 25. J Med Chem. 2017. PMID: 28686445

7

Discovery of Novel Pyrazolopyrimidinone Derivatives as Phosphodiesterase 9A Inhibitors Capable of Inhibiting Butyrylcholinesterase for Treatment of Alzheimer's Disease.

Yu YF, Huang YD, Zhang C, Wu XN, Zhou Q, Wu D, Wu Y, Luo HB. Yu YF, et al. Among authors: wu y, wu d, wu xn. ACS Chem Neurosci. 2017 Nov 15;8(11):2522-2534. doi: 10.1021/acschemneuro.7b00268. Epub 2017 Aug 23. ACS Chem Neurosci. 2017. PMID: 28783948

8

Docking-assisted 3D-QSAR studies on xanthones as α-glucosidase inhibitors.

Zheng X, Zhou S, Zhang C, Wu D, Luo HB, Wu Y. Zheng X, et al. Among authors: wu y, wu d. J Mol Model. 2017 Aug 31;23(9):272. doi: 10.1007/s00894-017-3438-1. J Mol Model. 2017. PMID: 28861624

9

Discovery of novel purine nucleoside derivatives as phosphodiesterase 2 (PDE2) inhibitors: Structure-based virtual screening, optimization and biological evaluation.

Qiu X, Huang Y, Wu D, Mao F, Zhu J, Yan W, Luo HB, Li J. Qiu X, et al. Among authors: wu d. Bioorg Med Chem. 2018 Jan 1;26(1):119-133. doi: 10.1016/j.bmc.2017.11.022. Epub 2017 Nov 14. Bioorg Med Chem. 2018. PMID: 29174506

10

Novel Phosphodiesterase Inhibitors for Cognitive Improvement in Alzheimer's Disease.

Wu Y, Li Z, Huang YY, Wu D, Luo HB. Wu Y, et al. Among authors: wu d. J Med Chem. 2018 Jul 12;61(13):5467-5483. doi: 10.1021/acs.jmedchem.7b01370. Epub 2018 Feb 5. J Med Chem. 2018. PMID: 29363967 Review.

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