O'Brien NA - Search Results

1

Correction: Targeting ErbB-2 nuclear localization and function inhibits breast cancer growth and overcomes trastuzumab resistance.

Russo RIC, Béguelin W, Flaqué MCD, Proietti CJ, Venturutti L, Galigniana N, Tkach M, Guzmán P, Roa JC, O'Brien NA, Charreau EH, Schillaci R, Elizalde PV. Russo RIC, et al. Among authors: o brien na. Oncogene. 2023 Oct;42(42):3157-3158. doi: 10.1038/s41388-023-02832-1. Oncogene. 2023. PMID: 37684410 No abstract available.

2

Targeting ErbB-2 nuclear localization and function inhibits breast cancer growth and overcomes trastuzumab resistance.

Cordo Russo RI, Béguelin W, Díaz Flaqué MC, Proietti CJ, Venturutti L, Galigniana N, Tkach M, Guzmán P, Roa JC, O'Brien NA, Charreau EH, Schillaci R, Elizalde PV. Cordo Russo RI, et al. Oncogene. 2015 Jun;34(26):3413-28. doi: 10.1038/onc.2014.272. Epub 2014 Sep 1. Oncogene. 2015. PMID: 25174405

3

Dacomitinib (PF-00299804), an irreversible Pan-HER inhibitor, inhibits proliferation of HER2-amplified breast cancer cell lines resistant to trastuzumab and lapatinib.

Kalous O, Conklin D, Desai AJ, O'Brien NA, Ginther C, Anderson L, Cohen DJ, Britten CD, Taylor I, Christensen JG, Slamon DJ, Finn RS. Kalous O, et al. Mol Cancer Ther. 2012 Sep;11(9):1978-87. doi: 10.1158/1535-7163.MCT-11-0730. Epub 2012 Jul 3. Mol Cancer Ther. 2012. PMID: 22761403

4

Tucatinib has Selective Activity in HER2-Positive Cancers and Significant Combined Activity with Approved and Novel Breast Cancer-Targeted Therapies.

O'Brien NA, Huang HKT, McDermott MSJ, Madrid AM, Luo T, Ayala R, Issakhanian S, Gong KW, Lu M, Zhang J, Slamon DJ. O'Brien NA, et al. Mol Cancer Ther. 2022 May 4;21(5):751-761. doi: 10.1158/1535-7163.MCT-21-0847. Mol Cancer Ther. 2022. PMID: 35417017

5

Activated phosphoinositide 3-kinase/AKT signaling confers resistance to trastuzumab but not lapatinib.

O'Brien NA, Browne BC, Chow L, Wang Y, Ginther C, Arboleda J, Duffy MJ, Crown J, O'Donovan N, Slamon DJ. O'Brien NA, et al. Mol Cancer Ther. 2010 Jun;9(6):1489-502. doi: 10.1158/1535-7163.MCT-09-1171. Epub 2010 May 25. Mol Cancer Ther. 2010. PMID: 20501798

6

Inhibition of HSP90 with AUY922 induces synergy in HER2-amplified trastuzumab-resistant breast and gastric cancer.

Wainberg ZA, Anghel A, Rogers AM, Desai AJ, Kalous O, Conklin D, Ayala R, O'Brien NA, Quadt C, Akimov M, Slamon DJ, Finn RS. Wainberg ZA, et al. Mol Cancer Ther. 2013 Apr;12(4):509-19. doi: 10.1158/1535-7163.MCT-12-0507. Epub 2013 Feb 8. Mol Cancer Ther. 2013. PMID: 23395886

7

Dual inhibition of IGF1R and ER enhances response to trastuzumab in HER2 positive breast cancer cells.

McDermott MSJ, Canonici A, Ivers L, Browne BC, Madden SF, O'Brien NA, Crown J, O'Donovan N. McDermott MSJ, et al. Int J Oncol. 2017 Jun;50(6):2221-2228. doi: 10.3892/ijo.2017.3976. Epub 2017 Apr 26. Int J Oncol. 2017. PMID: 28498399

8

Correction: PP2A inhibition overcomes acquired resistance to HER2 targeted therapy.

McDermott MSJ, Browne BC, Conlon NT, O'Brien NA, Slamon DJ, Henry M, Meleady P, Clynes M, Dowling P, Crown J, O'Donovan N. McDermott MSJ, et al. Among authors: o brien na. Mol Cancer. 2023 Oct 30;22(1):175. doi: 10.1186/s12943-023-01890-z. Mol Cancer. 2023. PMID: 37915024 Free PMC article. No abstract available.

9

The HSP90 inhibitor NVP-AUY922 inhibits growth of HER2 positive and trastuzumab-resistant breast cancer cells.

Canonici A, Qadir Z, Conlon NT, Collins DM, O'Brien NA, Walsh N, Eustace AJ, O'Donovan N, Crown J. Canonici A, et al. Invest New Drugs. 2018 Aug;36(4):581-589. doi: 10.1007/s10637-017-0556-7. Epub 2018 Feb 2. Invest New Drugs. 2018. PMID: 29396630

10

HER-targeted tyrosine kinase inhibitors enhance response to trastuzumab and pertuzumab in HER2-positive breast cancer.

Canonici A, Ivers L, Conlon NT, Pedersen K, Gaynor N, Browne BC, O'Brien NA, Gullo G, Collins DM, O'Donovan N, Crown J. Canonici A, et al. Invest New Drugs. 2019 Jun;37(3):441-451. doi: 10.1007/s10637-018-0649-y. Epub 2018 Jul 30. Invest New Drugs. 2019. PMID: 30062574

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