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PLK1 inhibition dampens NLRP3 inflammasome-elicited response in inflammatory disease models.
Baldrighi M, Doreth C, Li Y, Zhao X, Warner E, Chenoweth H, Kishore K, Umrania Y, Minde DP, Thome S, Yu X, Lu Y, Knapton A, Harrison J, Clarke M, Latz E, de Cárcer G, Malumbres M, Ryffel B, Bryant C, Liu J, Lilley KS, Mallat Z, Li X. Baldrighi M, et al. Among authors: zhao x. J Clin Invest. 2023 Nov 1;133(21):e162129. doi: 10.1172/JCI162129. J Clin Invest. 2023. PMID: 37698938 Free PMC article.
Marginal zone B cells produce 'natural' atheroprotective IgM antibodies in a T cell-dependent manner.
Harrison J, Newland SA, Jiang W, Giakomidi D, Zhao X, Clement M, Masters L, Corovic A, Zhang X, Drago F, Ma M, Ozsvar Kozma M, Yasin F, Saady Y, Kothari H, Zhao TX, Shi GP, McNamara CA, Binder CJ, Sage AP, Tarkin JM, Mallat Z, Nus M. Harrison J, et al. Among authors: zhao x, zhao tx. Cardiovasc Res. 2024 Mar 14;120(3):318-328. doi: 10.1093/cvr/cvae027. Cardiovasc Res. 2024. PMID: 38381113 Free PMC article.
GDF15 antagonism limits severe heart failure and prevents cardiac cachexia.
Takaoka M, Tadross JA, Al-Hadithi ABAK, Zhao X, Villena-Gutiérrez R, Tromp J, Absar S, Au M, Harrison J, Coll AP, Marciniak SJ, Rimmington D, Oliver E, Ibáñez B, Voors AA, O'Rahilly S, Mallat Z, Goodall JC. Takaoka M, et al. Among authors: zhao x. Cardiovasc Res. 2024 Sep 23:cvae214. doi: 10.1093/cvr/cvae214. Online ahead of print. Cardiovasc Res. 2024. PMID: 39312445
Coronavirus disease 2019-related myocardial injury is associated with immune dysregulation in symptomatic patients with cardiac magnetic resonance imaging abnormalities.
Ćorović A, Zhao X, Huang Y, Newland SR, Gopalan D, Harrison J, Giakomidi D, Chen S, Yarkoni NS, Wall C, Peverelli M, Sriranjan R, Gallo A, Graves MJ, Sage A, Lyons PA, Sithole N, Bennett MR, Rudd JHF, Mallat Z, Zhao TX, Nus M, Tarkin JM. Ćorović A, et al. Among authors: zhao x, zhao tx. Cardiovasc Res. 2024 Nov 25;120(14):1752-1767. doi: 10.1093/cvr/cvae159. Cardiovasc Res. 2024. PMID: 39073768 Free PMC article.
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