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Natural human Bet v 1-specific IgG antibodies recognize non-conformational epitopes whereas IgE reacts with conformational epitopes.
Brazhnikov G, Smolnikov E, Litovkina A, Jiang T, Shatilov A, Tulaeva I, Tulaev M, Karaulov A, Poroshina A, Zhernov Y, Focke-Tejkl M, Weber M, Akinfenwa O, Elisyutina O, Andreev S, Shilovskiy I, Shershakova N, Smirnov V, Fedenko E, Lepeshkova TS, Beltyukov EC, Naumova VV, Kundi M, Khaitov M, Wiedermann U, Valenta R, Campana R. Brazhnikov G, et al. Among authors: campana r. Allergy. 2023 Dec;78(12):3136-3153. doi: 10.1111/all.15865. Epub 2023 Sep 13. Allergy. 2023. PMID: 37701941 Free PMC article.
Cigarette smoke facilitates allergen penetration across respiratory epithelium.
Gangl K, Reininger R, Bernhard D, Campana R, Pree I, Reisinger J, Kneidinger M, Kundi M, Dolznig H, Thurnher D, Valent P, Chen KW, Vrtala S, Spitzauer S, Valenta R, Niederberger V. Gangl K, et al. Among authors: campana r. Allergy. 2009 Mar;64(3):398-405. doi: 10.1111/j.1398-9995.2008.01861.x. Epub 2008 Dec 16. Allergy. 2009. PMID: 19120070
A combination vaccine for allergy and rhinovirus infections based on rhinovirus-derived surface protein VP1 and a nonallergenic peptide of the major timothy grass pollen allergen Phl p 1.
Edlmayr J, Niespodziana K, Linhart B, Focke-Tejkl M, Westritschnig K, Scheiblhofer S, Stoecklinger A, Kneidinger M, Valent P, Campana R, Thalhamer J, Popow-Kraupp T, Valenta R. Edlmayr J, et al. Among authors: campana r. J Immunol. 2009 May 15;182(10):6298-306. doi: 10.4049/jimmunol.0713622. J Immunol. 2009. PMID: 19414783
Hypoallergenic derivatives of the major birch pollen allergen Bet v 1 obtained by rational sequence reassembly.
Campana R, Vrtala S, Maderegger B, Jertschin P, Stegfellner G, Swoboda I, Focke-Tejkl M, Blatt K, Gieras A, Zafred D, Neubauer A, Valent P, Keller W, Spitzauer S, Valenta R. Campana R, et al. J Allergy Clin Immunol. 2010 Nov;126(5):1024-31, 1031.e1-8. doi: 10.1016/j.jaci.2010.05.023. Epub 2010 Jul 16. J Allergy Clin Immunol. 2010. PMID: 20638112
Altered IgE epitope presentation: A model for hypoallergenic activity revealed for Bet v 1 trimer.
Campana R, Vrtala S, Maderegger B, Dall'Antonia Y, Zafred D, Blatt K, Herrmann H, Focke-Tejkl M, Swoboda I, Scheiblhofer S, Gieras A, Neubauer A, Keller W, Valent P, Thalhamer J, Spitzauer S, Valenta R. Campana R, et al. Mol Immunol. 2011 Jan;48(4):431-41. doi: 10.1016/j.molimm.2010.09.016. Epub 2010 Nov 18. Mol Immunol. 2011. PMID: 21093057 Free PMC article.
125 results