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Human OPRM1 and murine Oprm1 promoter driven viral constructs for genetic access to μ-opioidergic cell types.
Salimando GJ, Tremblay S, Kimmey BA, Li J, Rogers SA, Wojick JA, McCall NM, Wooldridge LM, Rodrigues A, Borner T, Gardiner KL, Jayakar SS, Singeç I, Woolf CJ, Hayes MR, De Jonghe BC, Bennett FC, Bennett ML, Blendy JA, Platt ML, Creasy KT, Renthal WR, Ramakrishnan C, Deisseroth K, Corder G. Salimando GJ, et al. Among authors: woolf cj. Nat Commun. 2023 Sep 13;14(1):5632. doi: 10.1038/s41467-023-41407-2. Nat Commun. 2023. PMID: 37704594 Free PMC article.
Developing nociceptor-selective treatments for acute and chronic pain.
Jayakar S, Shim J, Jo S, Bean BP, Singeç I, Woolf CJ. Jayakar S, et al. Among authors: woolf cj. Sci Transl Med. 2021 Nov 10;13(619):eabj9837. doi: 10.1126/scitranslmed.abj9837. Epub 2021 Nov 10. Sci Transl Med. 2021. PMID: 34757806 Free PMC article.
The oncomodulin receptor ArmC10 enables axon regeneration in mice after nerve injury and neurite outgrowth in human iPSC-derived sensory neurons.
Xie L, Yin Y, Jayakar S, Kawaguchi R, Wang Q, Peterson S, Shi C, Turnes BL, Zhang Z, Oses-Prieto J, Li J, Burlingame A, Woolf CJ, Geschwind D, Rasband M, Benowitz LI. Xie L, et al. Among authors: woolf cj. Sci Transl Med. 2023 Aug 9;15(708):eadg6241. doi: 10.1126/scitranslmed.adg6241. Epub 2023 Aug 9. Sci Transl Med. 2023. PMID: 37556559
The secondary somatosensory cortex gates mechanical and heat sensitivity.
Taub DG, Jiang Q, Pietrafesa F, Su J, Carroll A, Greene C, Blanchard MR, Jain A, El-Rifai M, Callen A, Yager K, Chung C, He Z, Chen C, Woolf CJ. Taub DG, et al. Among authors: woolf cj. Nat Commun. 2024 Feb 12;15(1):1289. doi: 10.1038/s41467-024-45729-7. Nat Commun. 2024. PMID: 38346995 Free PMC article.
Nociceptor-immune interactomes reveal insult-specific immune signatures of pain.
Jain A, Gyori BM, Hakim S, Jain A, Sun L, Petrova V, Bhuiyan SA, Zhen S, Wang Q, Kawaguchi R, Bunga S, Taub DG, Ruiz-Cantero MC, Tong-Li C, Andrews N, Kotoda M, Renthal W, Sorger PK, Woolf CJ. Jain A, et al. Among authors: woolf cj. Nat Immunol. 2024 Jul;25(7):1296-1305. doi: 10.1038/s41590-024-01857-2. Epub 2024 May 28. Nat Immunol. 2024. PMID: 38806708 Free PMC article.
452 results