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The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects {beta}-cells against stress-induced apoptosis.
Baquié M, St-Onge L, Kerr-Conte J, Cobo-Vuilleumier N, Lorenzo PI, Jimenez Moreno CM, Cederroth CR, Nef S, Borot S, Bosco D, Wang H, Marchetti P, Pattou F, Wollheim CB, Gauthier BR. Baquié M, et al. Among authors: lorenzo pi. Hum Mol Genet. 2011 Jul 15;20(14):2823-33. doi: 10.1093/hmg/ddr193. Epub 2011 May 2. Hum Mol Genet. 2011. PMID: 21536586
A Simple High Efficiency Intra-Islet Transduction Protocol Using Lentiviral Vectors.
Jimenez-Moreno CM, Herrera-Gomez IG, Lopez-Noriega L, Lorenzo PI, Cobo-Vuilleumier N, Fuente-Martin E, Mellado-Gil JM, Parnaud G, Bosco D, Gauthier BR, Martin-Montalvo A. Jimenez-Moreno CM, et al. Among authors: lorenzo pi. Curr Gene Ther. 2015;15(4):436-46. doi: 10.2174/1566523215666150630121557. Curr Gene Ther. 2015. PMID: 26122098 Free PMC article.
PAX4 Defines an Expandable β-Cell Subpopulation in the Adult Pancreatic Islet.
Lorenzo PI, Fuente-Martín E, Brun T, Cobo-Vuilleumier N, Jimenez-Moreno CM, G Herrera Gomez I, López Noriega L, Mellado-Gil JM, Martin-Montalvo A, Soria B, Gauthier BR. Lorenzo PI, et al. Sci Rep. 2015 Oct 27;5:15672. doi: 10.1038/srep15672. Sci Rep. 2015. PMID: 26503027 Free PMC article.
PAX4 preserves endoplasmic reticulum integrity preventing beta cell degeneration in a mouse model of type 1 diabetes mellitus.
Mellado-Gil JM, Jiménez-Moreno CM, Martin-Montalvo A, Alvarez-Mercado AI, Fuente-Martin E, Cobo-Vuilleumier N, Lorenzo PI, Bru-Tari E, Herrera-Gómez Ide G, López-Noriega L, Pérez-Florido J, Santoyo-López J, Spyrantis A, Meda P, Boehm BO, Quesada I, Gauthier BR. Mellado-Gil JM, et al. Among authors: lorenzo pi. Diabetologia. 2016 Apr;59(4):755-65. doi: 10.1007/s00125-016-3864-0. Epub 2016 Jan 26. Diabetologia. 2016. PMID: 26813254 Free PMC article.
40 results