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Activation of the transcription factor NFAT5 in the tumor microenvironment enforces CD8+ T cell exhaustion.
Tillé L, Cropp D, Charmoy M, Reichenbach P, Andreatta M, Wyss T, Bodley G, Crespo I, Nassiri S, Lourenco J, Leblond MM, Lopez-Rodriguez C, Speiser DE, Coukos G, Irving M, Carmona SJ, Held W, Verdeil G. Tillé L, et al. Among authors: reichenbach p. Nat Immunol. 2023 Oct;24(10):1645-1653. doi: 10.1038/s41590-023-01614-x. Epub 2023 Sep 14. Nat Immunol. 2023. PMID: 37709986
TCR sequencing and cloning methods for repertoire analysis and isolation of tumor-reactive TCRs.
Genolet R, Bobisse S, Chiffelle J, Arnaud M, Petremand R, Queiroz L, Michel A, Reichenbach P, Cesbron J, Auger A, Baumgaertner P, Guillaume P, Schmidt J, Irving M, Kandalaft LE, Speiser DE, Coukos G, Harari A. Genolet R, et al. Among authors: reichenbach p. Cell Rep Methods. 2023 Apr 24;3(4):100459. doi: 10.1016/j.crmeth.2023.100459. eCollection 2023 Apr 24. Cell Rep Methods. 2023. PMID: 37159666 Free PMC article.
Dual ON/OFF-switch chimeric antigen receptor controlled by two clinically approved drugs.
Giordano Attianese GMP, Shui S, Cribioli E, Triboulet M, Scheller L, Hafezi M, Reichenbach P, Gainza P, Georgeon S, Correia BE, Irving M. Giordano Attianese GMP, et al. Among authors: reichenbach p. Proc Natl Acad Sci U S A. 2024 Oct 29;121(44):e2405085121. doi: 10.1073/pnas.2405085121. Epub 2024 Oct 25. Proc Natl Acad Sci U S A. 2024. PMID: 39453747 Free PMC article.
Structure-based optimization of type III indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors.
Röhrig UF, Majjigapu SR, Vogel P, Reynaud A, Pojer F, Dilek N, Reichenbach P, Ascenção K, Irving M, Coukos G, Michielin O, Zoete V. Röhrig UF, et al. Among authors: reichenbach p. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1773-1811. doi: 10.1080/14756366.2022.2089665. J Enzyme Inhib Med Chem. 2022. PMID: 35758198 Free PMC article.
Azole-Based Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors.
Röhrig UF, Majjigapu SR, Reynaud A, Pojer F, Dilek N, Reichenbach P, Ascencao K, Irving M, Coukos G, Vogel P, Michielin O, Zoete V. Röhrig UF, et al. Among authors: reichenbach p. J Med Chem. 2021 Feb 25;64(4):2205-2227. doi: 10.1021/acs.jmedchem.0c01968. Epub 2021 Feb 8. J Med Chem. 2021. PMID: 33557523
Author Correction: A computationally designed chimeric antigen receptor provides a small-molecule safety switch for T-cell therapy.
Giordano-Attianese G, Gainza P, Gray-Gaillard E, Cribioli E, Shui S, Kim S, Kwak MJ, Vollers S, Corria Osorio AJ, Reichenbach P, Bonet J, Oh BH, Irving M, Coukos G, Correia BE. Giordano-Attianese G, et al. Among authors: reichenbach p. Nat Biotechnol. 2020 Apr;38(4):503. doi: 10.1038/s41587-020-0461-z. Nat Biotechnol. 2020. PMID: 32127717
48 results