Whisstock JC - Search Results

1

Fragment-based and structure-guided discovery of perforin inhibitors.

Jose J, Law RHP, Leung EWW, Wai DCC, Akhlaghi H, Chandrashekaran IR, Caradoc-Davies TT, Voskoboinik I, Feutrill J, Middlemiss D, Jeevarajah D, Bashtannyk-Puhalovich T, Giddens AC, Lee TW, Jamieson SMF, Trapani JA, Whisstock JC, Spicer JA, Norton RS. Jose J, et al. Among authors: whisstock jc. Eur J Med Chem. 2023 Dec 5;261:115786. doi: 10.1016/j.ejmech.2023.115786. Epub 2023 Sep 1. Eur J Med Chem. 2023. PMID: 37716187 Free article.

2

Design of Polarity-Dependent Immunosensors Based on the Structural Analysis of Engineered Antibodies.

Islam J, Conroy P, Fercher C, Kim M, Yaari Z, Jones M, Bell TDM, Caradoc-Davies T, Law R, Whisstock J, Heller D, Mahler S, Corrie S. Islam J, et al. ACS Chem Biol. 2023 Aug 18;18(8):1863-1871. doi: 10.1021/acschembio.3c00303. Epub 2023 Jul 13. ACS Chem Biol. 2023. PMID: 37440171

3

A High-Throughput Small-Angle X-ray Scattering Assay to Determine the Conformational Change of Plasminogen.

Quek AJ, Cowieson NP, Caradoc-Davies TT, Conroy PJ, Whisstock JC, Law RHP. Quek AJ, et al. Among authors: whisstock jc. Int J Mol Sci. 2023 Sep 19;24(18):14258. doi: 10.3390/ijms241814258. Int J Mol Sci. 2023. PMID: 37762561 Free PMC article.

4

Proteoform-Resolved Profiling of Plasminogen Activation Reveals Novel Abundant Phosphorylation Site and Primary N-Terminal Cleavage Site.

Cramer DAT, Yin V, Caval T, Franc V, Yu D, Wu G, Lloyd G, Langendorf C, Whisstock JC, Law RHP, Heck AJR. Cramer DAT, et al. Among authors: whisstock jc. Mol Cell Proteomics. 2024 Jan;23(1):100696. doi: 10.1016/j.mcpro.2023.100696. Epub 2023 Dec 13. Mol Cell Proteomics. 2024. PMID: 38101751 Free PMC article.

5

Macrocyclic Inhibitors Targeting the Prime Site of the Fibrinolytic Serine Protease Plasmin.

Wiedemeyer SJA, Wu G, Lang-Henkel H, Whisstock JC, Law RHP, Steinmetzer T. Wiedemeyer SJA, et al. Among authors: whisstock jc. ChemMedChem. 2024 Dec 2;19(23):e202400360. doi: 10.1002/cmdc.202400360. Epub 2024 Sep 30. ChemMedChem. 2024. PMID: 39118493 Free PMC article.

6

OpenFIBSEM: A universal API for FIBSEM control.

Cleeve P, Dierickx D, Naegele L, Kannachel R, Burne L, Buckley G, Gorelick S, Whisstock JC, de Marco A. Cleeve P, et al. Among authors: whisstock jc. J Struct Biol. 2023 Sep;215(3):107967. doi: 10.1016/j.jsb.2023.107967. Epub 2023 Apr 25. J Struct Biol. 2023. PMID: 37105276 Free article.

7

TcpA from the Clostridium perfringens plasmid pCW3 is more closely related to the DNA translocase FtsK than to coupling proteins.

Traore DAK, Torres VVL, Akhtar N, Gummer AM, Flanigan SF, Coulibaly F, Adams V, Whisstock JC, Rood JI. Traore DAK, et al. Among authors: whisstock jc. Structure. 2023 Apr 6;31(4):455-463.e4. doi: 10.1016/j.str.2023.02.001. Epub 2023 Feb 24. Structure. 2023. PMID: 36841236 Free article.

8

[No title available]

[No authors listed] [No authors listed] PMID: 37612925

9

Patients with Waldenström macroglobulinemia have impaired platelet and coagulation function.

Brysland SA, Talaulikar D, Hicks SM, Hearn JI, Ali SA, Maqbool MG, Mokoonlall M, Bhoopalan V, Kaur A, Thong YL, Andrews RK, Whisstock JC, Crispin PJ, Gardiner EE. Brysland SA, et al. Among authors: whisstock jc. Blood Adv. 2024 Nov 12;8(21):5542-5555. doi: 10.1182/bloodadvances.2024014190. Blood Adv. 2024. PMID: 39207869 Free PMC article.

10

The role of NINJ1 protein in programmed cellular destruction.

Whisstock JC, Law RHP. Whisstock JC, et al. Nature. 2023 Jun;618(7967):912-914. doi: 10.1038/d41586-023-01602-z. Nature. 2023. PMID: 37198463 No abstract available.

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