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Increased MCL1 dependency leads to new applications of BH3-mimetics in drug-resistant neuroblastoma.
Jacob M, Wiedemann S, Brücher D, Pieper NM, Birkhold M, Särchen V, Jeroch J, Demes MC, Gretser S, Braun Y, Gradhand E, Rothweiler F, Michaelis M, Cinatl J Jr, Vogler M. Jacob M, et al. Among authors: rothweiler f. Br J Cancer. 2023 Nov;129(10):1667-1678. doi: 10.1038/s41416-023-02430-8. Epub 2023 Sep 19. Br J Cancer. 2023. PMID: 37723317 Free PMC article.
Cisplatin-resistant neuroblastoma cells express enhanced levels of epidermal growth factor receptor (EGFR) and are sensitive to treatment with EGFR-specific toxins.
Michaelis M, Bliss J, Arnold SC, Hinsch N, Rothweiler F, Deubzer HE, Witt O, Langer K, Doerr HW, Wels WS, Cinatl J Jr. Michaelis M, et al. Among authors: rothweiler f. Clin Cancer Res. 2008 Oct 15;14(20):6531-7. doi: 10.1158/1078-0432.CCR-08-0821. Clin Cancer Res. 2008. PMID: 18927293 Free article.
Anti-cancer effects of artesunate in a panel of chemoresistant neuroblastoma cell lines.
Michaelis M, Kleinschmidt MC, Barth S, Rothweiler F, Geiler J, Breitling R, Mayer B, Deubzer H, Witt O, Kreuter J, Doerr HW, Cinatl J, Cinatl J Jr. Michaelis M, et al. Among authors: rothweiler f. Biochem Pharmacol. 2010 Jan 15;79(2):130-6. doi: 10.1016/j.bcp.2009.08.013. Epub 2009 Aug 19. Biochem Pharmacol. 2010. PMID: 19698702
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