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Reduction in mitochondrial iron alleviates cardiac damage during injury.
Chang HC, Wu R, Shang M, Sato T, Chen C, Shapiro JS, Liu T, Thakur A, Sawicki KT, Prasad SV, Ardehali H. Chang HC, et al. Among authors: chen c. EMBO Mol Med. 2016 Mar 1;8(3):247-67. doi: 10.15252/emmm.201505748. EMBO Mol Med. 2016. PMID: 26896449 Free PMC article.
Sirtuin 2 regulates cellular iron homeostasis via deacetylation of transcription factor NRF2.
Yang X, Park SH, Chang HC, Shapiro JS, Vassilopoulos A, Sawicki KT, Chen C, Shang M, Burridge PW, Epting CL, Wilsbacher LD, Jenkitkasemwong S, Knutson M, Gius D, Ardehali H. Yang X, et al. Among authors: chen c. J Clin Invest. 2017 Apr 3;127(4):1505-1516. doi: 10.1172/JCI88574. Epub 2017 Mar 13. J Clin Invest. 2017. PMID: 28287409 Free PMC article.
mRNA-binding protein tristetraprolin is essential for cardiac response to iron deficiency by regulating mitochondrial function.
Sato T, Chang HC, Bayeva M, Shapiro JS, Ramos-Alonso L, Kouzu H, Jiang X, Liu T, Yar S, Sawicki KT, Chen C, Martínez-Pastor MT, Stumpo DJ, Schumacker PT, Blackshear PJ, Ben-Sahra I, Puig S, Ardehali H. Sato T, et al. Among authors: chen c. Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):E6291-E6300. doi: 10.1073/pnas.1804701115. Epub 2018 Jun 18. Proc Natl Acad Sci U S A. 2018. PMID: 29915044 Free PMC article.
Hexokinase 1 cellular localization regulates the metabolic fate of glucose.
De Jesus A, Keyhani-Nejad F, Pusec CM, Goodman L, Geier JA, Stoolman JS, Stanczyk PJ, Nguyen T, Xu K, Suresh KV, Chen Y, Rodriguez AE, Shapiro JS, Chang HC, Chen C, Shah KP, Ben-Sahra I, Layden BT, Chandel NS, Weinberg SE, Ardehali H. De Jesus A, et al. Among authors: chen c, chen y. Mol Cell. 2022 Apr 7;82(7):1261-1277.e9. doi: 10.1016/j.molcel.2022.02.028. Epub 2022 Mar 18. Mol Cell. 2022. PMID: 35305311 Free PMC article.
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