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A multi-laboratory preclinical trial in rodents to assess treatment candidates for acute ischemic stroke.
Lyden PD, Diniz MA, Bosetti F, Lamb J, Nagarkatti KA, Rogatko A, Kim S, Cabeen RP, Koenig JI, Akhter K, Arbab AS, Avery BD, Beatty HE, Bibic A, Cao S, Simoes Braga Boisserand L, Chamorro A, Chauhan A, Diaz-Perez S, Dhandapani K, Dhanesha N, Goh A, Herman AL, Hyder F, Imai T, Johnson CW, Khan MB, Kamat P, Karuppagounder SS, Kumskova M, Mihailovic JM, Mandeville JB, Morais A, Patel RB, Sanganahalli BG, Smith C, Shi Y, Sutariya B, Thedens D, Qin T, Velazquez SE, Aronowski J, Ayata C, Chauhan AK, Leira EC, Hess DC, Koehler RC, McCullough LD, Sansing LH. Lyden PD, et al. Among authors: simoes braga boisserand l. Sci Transl Med. 2023 Sep 20;15(714):eadg8656. doi: 10.1126/scitranslmed.adg8656. Epub 2023 Sep 20. Sci Transl Med. 2023. PMID: 37729432 Clinical Trial.
VEGF-C promotes brain-derived fluid drainage, confers neuroprotection, and improves stroke outcomes.
Simoes Braga Boisserand L, Bouchart J, Geraldo LH, Lee S, Sanganahalli BG, Parent M, Zhang S, Xue Y, Skarica M, Guegan J, Li M, Liu X, Poulet M, Askanase M, Osherov A, Spajer M, Kamouh ME, Eichmann A, Alitalo K, Zhou J, Sestan N, Sansing LH, Benveniste H, Hyder F, Thomas JL. Simoes Braga Boisserand L, et al. bioRxiv [Preprint]. 2023 May 30:2023.05.30.542708. doi: 10.1101/2023.05.30.542708. bioRxiv. 2023. PMID: 37398128 Free PMC article. Preprint.