Hargreaves DC - Search Results

1

Manipulating mitochondrial electron flow enhances tumor immunogenicity.

Mangalhara KC, Varanasi SK, Johnson MA, Burns MJ, Rojas GR, Esparza Moltó PB, Sainz AG, Tadepalle N, Abbott KL, Mendiratta G, Chen D, Farsakoglu Y, Kunchok T, Hoffmann FA, Parisi B, Rincon M, Vander Heiden MG, Bosenberg M, Hargreaves DC, Kaech SM, Shadel GS. Mangalhara KC, et al. Among authors: hargreaves dc. Science. 2023 Sep 22;381(6664):1316-1323. doi: 10.1126/science.abq1053. Epub 2023 Sep 21. Science. 2023. PMID: 37733872 Free PMC article.

2

BRD9 regulates interferon-stimulated genes during macrophage activation via cooperation with BET protein BRD4.

Ahmed NS, Gatchalian J, Ho J, Burns MJ, Hah N, Wei Z, Downes M, Evans RM, Hargreaves DC. Ahmed NS, et al. Among authors: hargreaves dc. Proc Natl Acad Sci U S A. 2022 Jan 4;119(1):e2110812119. doi: 10.1073/pnas.2110812119. Proc Natl Acad Sci U S A. 2022. PMID: 34983841 Free PMC article.

3

Canonical BAF complex activity shapes the enhancer landscape that licenses CD8⁺ T cell effector and memory fates.

McDonald B, Chick BY, Ahmed NS, Burns M, Ma S, Casillas E, Chen D, Mann TH, O'Connor C, Hah N, Hargreaves DC, Kaech SM. McDonald B, et al. Among authors: hargreaves dc. Immunity. 2023 Jun 13;56(6):1303-1319.e5. doi: 10.1016/j.immuni.2023.05.005. Immunity. 2023. PMID: 37315534 Free PMC article.

4

Early Chromatin Remodeling Events in Acutely Stimulated CD8⁺ T Cells.

McDonald B, Chick BY, Hargreaves DC, Kaech SM. McDonald B, et al. Among authors: hargreaves dc. Yale J Biol Med. 2023 Dec 29;96(4):467-473. doi: 10.59249/AXGU7370. eCollection 2023 Dec. Yale J Biol Med. 2023. PMID: 38161581 Free PMC article.

5

ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity.

Maxwell MB, Hom-Tedla MS, Yi J, Li S, Rivera SA, Yu J, Burns MJ, McRae HM, Stevenson BT, Coakley KE, Ho J, Gastelum KB, Bell JC, Jones AC, Eskander RN, Dykhuizen EC, Shadel GS, Kaech SM, Hargreaves DC. Maxwell MB, et al. Among authors: hargreaves dc. Cell. 2024 Jun 20;187(13):3390-3408.e19. doi: 10.1016/j.cell.2024.04.025. Epub 2024 May 15. Cell. 2024. PMID: 38754421

6

Collaboration between distinct SWI/SNF chromatin remodeling complexes directs enhancer selection and activation of macrophage inflammatory genes.

Liao J, Ho J, Burns M, Dykhuizen EC, Hargreaves DC. Liao J, et al. Among authors: hargreaves dc. Immunity. 2024 Aug 13;57(8):1780-1795.e6. doi: 10.1016/j.immuni.2024.05.008. Epub 2024 Jun 5. Immunity. 2024. PMID: 38843835

7

Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers.

Kelso TWR, Porter DK, Amaral ML, Shokhirev MN, Benner C, Hargreaves DC. Kelso TWR, et al. Among authors: hargreaves dc. Elife. 2017 Oct 2;6:e30506. doi: 10.7554/eLife.30506. Elife. 2017. PMID: 28967863 Free PMC article.

8

A Genome-wide CRISPR Screen Reveals a Role for the Non-canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell Function.

Loo CS, Gatchalian J, Liang Y, Leblanc M, Xie M, Ho J, Venkatraghavan B, Hargreaves DC, Zheng Y. Loo CS, et al. Among authors: hargreaves dc. Immunity. 2020 Jul 14;53(1):143-157.e8. doi: 10.1016/j.immuni.2020.06.011. Epub 2020 Jul 7. Immunity. 2020. PMID: 32640256 Free PMC article.

9

Transcription factor dependencies identify BAF-dependent cancers.

McRae HM, Hargreaves DC. McRae HM, et al. Among authors: hargreaves dc. Cancer Cell. 2024 Aug 12;42(8):1326-1328. doi: 10.1016/j.ccell.2024.06.013. Epub 2024 Jul 18. Cancer Cell. 2024. PMID: 39029465

10

Switching under selection: how CoREST controls endocrine therapy resistance in ER⁺ breast cancer.

Chick BY, Hargreaves DC. Chick BY, et al. Among authors: hargreaves dc. Nat Struct Mol Biol. 2022 Nov;29(11):1040-1042. doi: 10.1038/s41594-022-00858-9. Nat Struct Mol Biol. 2022. PMID: 36344845 No abstract available.

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