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Page 1
Mechanism of activation and biased signaling in complement receptor C5aR1.
Feng Y, Zhao C, Deng Y, Wang H, Ma L, Liu S, Tian X, Wang B, Bin Y, Chen P, Yan W, Fu P, Shao Z. Feng Y, et al. Among authors: tian x. Cell Res. 2023 Apr;33(4):312-324. doi: 10.1038/s41422-023-00779-2. Epub 2023 Feb 17. Cell Res. 2023. PMID: 36806352 Free PMC article.
Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.
Zhao C, Wang H, Liu Y, Cheng L, Wang B, Tian X, Fu H, Wu C, Li Z, Shen C, Yu J, Yang S, Hu H, Fu P, Ma L, Wang C, Yan W, Shao Z. Zhao C, et al. Among authors: tian x. Mol Cell. 2023 Sep 7;83(17):3171-3187.e7. doi: 10.1016/j.molcel.2023.07.030. Epub 2023 Aug 18. Mol Cell. 2023. PMID: 37597514 Free article.
Ligand recognition and G-protein coupling of trace amine receptor TAAR1.
Xu Z, Guo L, Yu J, Shen S, Wu C, Zhang W, Zhao C, Deng Y, Tian X, Feng Y, Hou H, Su L, Wang H, Guo S, Wang H, Wang K, Chen P, Zhao J, Zhang X, Yong X, Cheng L, Liu L, Yang S, Yang F, Wang X, Yu X, Xu Y, Sun JP, Yan W, Shao Z. Xu Z, et al. Among authors: tian x. Nature. 2023 Dec;624(7992):672-681. doi: 10.1038/s41586-023-06804-z. Epub 2023 Nov 7. Nature. 2023. PMID: 37935376
Structure, function and drug discovery of GPCR signaling.
Cheng L, Xia F, Li Z, Shen C, Yang Z, Hou H, Sun S, Feng Y, Yong X, Tian X, Qin H, Yan W, Shao Z. Cheng L, et al. Among authors: tian x. Mol Biomed. 2023 Dec 4;4(1):46. doi: 10.1186/s43556-023-00156-w. Mol Biomed. 2023. PMID: 38047990 Free PMC article. Review.
Structure-based identification of a G protein-biased allosteric modulator of cannabinoid receptor CB1.
Shen S, Wu C, Lin G, Yang X, Zhou Y, Zhao C, Miao Z, Tian X, Wang K, Yang Z, Liu Z, Guo N, Li Y, Xia A, Zhou P, Liu J, Yan W, Ke B, Yang S, Shao Z. Shen S, et al. Among authors: tian x. Proc Natl Acad Sci U S A. 2024 Jun 11;121(24):e2321532121. doi: 10.1073/pnas.2321532121. Epub 2024 Jun 3. Proc Natl Acad Sci U S A. 2024. PMID: 38830102 Free PMC article.
Entropy drives the ligand recognition in G-protein-coupled receptor subtypes.
Yang X, Zhou P, Shen S, Hu Q, Tian C, Xia A, Wang Y, Yang Z, Nan J, Zhou Y, Chen S, Tian X, Wu C, Lin G, Zhang L, Wang K, Zheng T, Zou J, Yan W, Shao Z, Yang S. Yang X, et al. Among authors: tian c, tian x. Proc Natl Acad Sci U S A. 2024 Jul 23;121(30):e2401091121. doi: 10.1073/pnas.2401091121. Epub 2024 Jul 18. Proc Natl Acad Sci U S A. 2024. PMID: 39024109 Free PMC article.
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