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Functional Overlap of Inborn Errors of Immunity and Metabolism Genes Define T Cell Immunometabolic Vulnerabilities.
Patterson AR, Needle GA, Sugiura A, Chi C, Steiner KK, Fisher EL, Robertson GL, Bodnya C, Markle JG, Gama V, Rathmell JC. Patterson AR, et al. Among authors: chi c. bioRxiv [Preprint]. 2023 Jan 24:2023.01.24.525419. doi: 10.1101/2023.01.24.525419. bioRxiv. 2023. Update in: Sci Immunol. 2024 Aug 16;9(98):eadh0368. doi: 10.1126/sciimmunol.adh0368 PMID: 36747715 Free PMC article. Updated. Preprint.
Differential Effects of Glutamine Inhibition Strategies on Antitumor CD8 T Cells.
Madden MZ, Ye X, Chi C, Fisher EL, Wolf MM, Needle GA, Bader JE, Patterson AR, Reinfeld BI, Landis MD, Hathaway ES, Muka JE, O'Neil RT, Karijolich J, Philip M, Rathmell JC. Madden MZ, et al. Among authors: chi c. J Immunol. 2023 Aug 15;211(4):563-575. doi: 10.4049/jimmunol.2200715. J Immunol. 2023. PMID: 37341499 Free PMC article.
Mitochondrial Fatty Acid Synthesis and Mecr Regulate CD4+ T Cell Function and Oxidative Metabolism.
Steiner KK, Young AC, Patterson AR, Jennings EQ, Chi C, Hatem Z, Heintzman D, Sugiura A, Arner EN, Sewell AE, Madden MZ, Okparaugo R, Fallman EV, Gibson-Corley K, Voss K, Mogilenko D, Rathmell J. Steiner KK, et al. Among authors: chi c. bioRxiv [Preprint]. 2024 Jul 11:2024.07.08.602554. doi: 10.1101/2024.07.08.602554. bioRxiv. 2024. PMID: 39026793 Free PMC article. Preprint.
Subset-specific mitochondrial stress and DNA damage shape T cell responses to fever and inflammation.
Heintzman DR, Sinard RC, Fisher EL, Ye X, Patterson AR, Elasy JH, Voss K, Chi C, Sugiura A, Rodriguez-Garcia GJ, Chowdhury NU, Arner EN, Krystoviak ES, Mason FM, Toudji YT, Steiner KK, Khan W, Olson LM, Jones AL, Hong HS, Bass L, Beier KL, Deng W, Lyssiotis CA, Newcomb DC, Bick AG, Rathmell WK, Wilson JT, Rathmell JC. Heintzman DR, et al. Among authors: chi c. Sci Immunol. 2024 Sep 20;9(99):eadp3475. doi: 10.1126/sciimmunol.adp3475. Epub 2024 Sep 20. Sci Immunol. 2024. PMID: 39303018
Androgen signaling restricts glutaminolysis to drive sex-specific Th17 metabolism in allergic airway inflammation.
Chowdhury NU, Cephus JY, Henriquez Pilier E, Wolf MM, Madden MZ, Kuehnle SN, McKernan KE, Jennings EQ, Arner EN, Heintzman DR, Chi C, Sugiura A, Stier MT, Voss K, Ye X, Scales K, Krystofiak ES, Gandhi VD, Guzy RD, Cahill KN, Sperling AI, Peebles RS Jr, Rathmell JC, Newcomb DC. Chowdhury NU, et al. Among authors: chi c. J Clin Invest. 2024 Oct 15;134(23):e177242. doi: 10.1172/JCI177242. J Clin Invest. 2024. PMID: 39404231 Free PMC article.
2,744 results