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Page 1
De novo purine metabolism is a metabolic vulnerability of cancers with low p16 expression.
Tangudu NK, Buj R, Wang H, Wang J, Cole AR, Uboveja A, Fang R, Amalric A, Sajjakulnukit P, Lyons MA, Cooper K, Hempel N, Snyder NW, Lyssiotis CA, Chandran UR, Aird KM. Tangudu NK, et al. Among authors: lyssiotis ca. bioRxiv [Preprint]. 2023 Sep 23:2023.07.15.549149. doi: 10.1101/2023.07.15.549149. bioRxiv. 2023. Update in: Cancer Res Commun. 2024 May 2;4(5):1174-1188. doi: 10.1158/2767-9764.CRC-23-0450 PMID: 37503050 Free PMC article. Updated. Preprint.
ER-associated degradation adapter Sel1L is required for CD8+ T cell function and memory formation following acute viral infection.
Correa-Medero LO, Jankowski SE, Hong HS, Armas ND, Vijendra AI, Reynolds MB, Fogo GM, Awad D, Dils AT, Inoki KA, Williams RG, Ye AM, Svezhova N, Gomez-Rivera F, Collins KL, O'Riordan MX, Sanderson TH, Lyssiotis CA, Carty SA. Correa-Medero LO, et al. Among authors: lyssiotis ca. Cell Rep. 2024 May 28;43(5):114156. doi: 10.1016/j.celrep.2024.114156. Epub 2024 Apr 29. Cell Rep. 2024. PMID: 38687642 Free PMC article.
Ras-dependent activation of BMAL2 regulates hypoxic metabolism in pancreatic cancer.
Maurer HC, Garcia-Curiel A, Holmstrom SR, Castillo C, Palermo CF, Sastra SA, Andren A, Zhang L, Le Large TYS, Sagalovskiy I, Ross DR, Wong W, Shaw K, Genkinger J, Manji GA, Iuga AC, Schmid RM, Johnson K, Badgley MA, Lyssiotis CA, Shah Y, Califano A, Olive KP. Maurer HC, et al. Among authors: lyssiotis ca. bioRxiv [Preprint]. 2024 Jun 22:2023.03.19.533333. doi: 10.1101/2023.03.19.533333. bioRxiv. 2024. PMID: 36993718 Free PMC article. Preprint.
Type I interferon governs immunometabolic checkpoints that coordinate inflammation during Staphylococcal infection.
Reynolds MB, Klein B, McFadden MJ, Judge NK, Navarrete HE, Michmerhuizen BC, Awad D, Schultz TL, Harms PW, Zhang L, O'Meara TR, Sexton JZ, Lyssiotis CA, Kahlenberg JM, O'Riordan MX. Reynolds MB, et al. Among authors: lyssiotis ca. Cell Rep. 2024 Aug 27;43(8):114607. doi: 10.1016/j.celrep.2024.114607. Epub 2024 Aug 9. Cell Rep. 2024. PMID: 39126652 Free PMC article.
Neutrophil glucose flux as a therapeutic target in antiphospholipid syndrome.
Tambralli A, Harbaugh A, NaveenKumar SK, Radyk MD, Rysenga CE, Sabb K, Hurley JM, Sule GJ, Yalavarthi S, Estes SK, Hoy CK, Smith T, Sarosh C, Madison JA, Schaefer JK, Sood SL, Zuo Y, Sawalha AH, Lyssiotis CA, Knight JS. Tambralli A, et al. Among authors: lyssiotis ca. J Clin Invest. 2024 Jun 13;134(15):e169893. doi: 10.1172/JCI169893. J Clin Invest. 2024. PMID: 38869951 Free PMC article.
203 results