Pyle AD - Search Results

1

Innate and adaptive AAV-mediated immune responses in a mouse model of Duchenne muscular dystrophy.

Emami MR, Espinoza A, Young CS, Ma F, Farahat PK, Felgner PL, Chamberlain JS, Xu X, Pyle AD, Pellegrini M, Villalta SA, Spencer MJ. Emami MR, et al. Among authors: pyle ad. Mol Ther Methods Clin Dev. 2023 Jun 12;30:90-102. doi: 10.1016/j.omtm.2023.06.002. eCollection 2023 Sep 14. Mol Ther Methods Clin Dev. 2023. PMID: 37746243 Free PMC article.

2

A Single CRISPR-Cas9 Deletion Strategy that Targets the Majority of DMD Patients Restores Dystrophin Function in hiPSC-Derived Muscle Cells.

Young CS, Hicks MR, Ermolova NV, Nakano H, Jan M, Younesi S, Karumbayaram S, Kumagai-Cresse C, Wang D, Zack JA, Kohn DB, Nakano A, Nelson SF, Miceli MC, Spencer MJ, Pyle AD. Young CS, et al. Among authors: pyle ad. Cell Stem Cell. 2016 Apr 7;18(4):533-40. doi: 10.1016/j.stem.2016.01.021. Epub 2016 Feb 11. Cell Stem Cell. 2016. PMID: 26877224 Free PMC article.

3

Exon Skipping Therapy.

Young CS, Pyle AD. Young CS, et al. Among authors: pyle ad. Cell. 2016 Nov 17;167(5):1144. doi: 10.1016/j.cell.2016.10.050. Cell. 2016. PMID: 27863231 Free article.

4

Creation of a Novel Humanized Dystrophic Mouse Model of Duchenne Muscular Dystrophy and Application of a CRISPR/Cas9 Gene Editing Therapy.

Young CS, Mokhonova E, Quinonez M, Pyle AD, Spencer MJ. Young CS, et al. Among authors: pyle ad. J Neuromuscul Dis. 2017;4(2):139-145. doi: 10.3233/JND-170218. J Neuromuscul Dis. 2017. PMID: 28505980 Free PMC article.

5

ERBB3 and NGFR mark a distinct skeletal muscle progenitor cell in human development and hPSCs.

Hicks MR, Hiserodt J, Paras K, Fujiwara W, Eskin A, Jan M, Xi H, Young CS, Evseenko D, Nelson SF, Spencer MJ, Handel BV, Pyle AD. Hicks MR, et al. Among authors: pyle ad. Nat Cell Biol. 2018 Jan;20(1):46-57. doi: 10.1038/s41556-017-0010-2. Epub 2017 Dec 18. Nat Cell Biol. 2018. PMID: 29255171 Free PMC article.

6

CRISPR for Neuromuscular Disorders: Gene Editing and Beyond.

Young CS, Pyle AD, Spencer MJ. Young CS, et al. Among authors: pyle ad. Physiology (Bethesda). 2019 Sep 1;34(5):341-353. doi: 10.1152/physiol.00012.2019. Physiology (Bethesda). 2019. PMID: 31389773 Free PMC article. Review.

7

A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells.

Xi H, Langerman J, Sabri S, Chien P, Young CS, Younesi S, Hicks M, Gonzalez K, Fujiwara W, Marzi J, Liebscher S, Spencer M, Van Handel B, Evseenko D, Schenke-Layland K, Plath K, Pyle AD. Xi H, et al. Among authors: pyle ad. Cell Stem Cell. 2020 Jul 2;27(1):158-176.e10. doi: 10.1016/j.stem.2020.04.017. Epub 2020 May 11. Cell Stem Cell. 2020. PMID: 32396864 Free PMC article.

8

A Small-Molecule Approach to Restore a Slow-Oxidative Phenotype and Defective CaMKIIβ Signaling in Limb Girdle Muscular Dystrophy.

Liu J, Campagna J, John V, Damoiseaux R, Mokhonova E, Becerra D, Meng H, McNally EM, Pyle AD, Kramerova I, Spencer MJ. Liu J, et al. Among authors: pyle ad. Cell Rep Med. 2020 Oct 20;1(7):100122. doi: 10.1016/j.xcrm.2020.100122. eCollection 2020 Oct 20. Cell Rep Med. 2020. PMID: 33205074 Free PMC article.

9

Genome Editing-Mediated Utrophin Upregulation in Duchenne Muscular Dystrophy Stem Cells.

Sengupta K, Mishra MK, Loro E, Spencer MJ, Pyle AD, Khurana TS. Sengupta K, et al. Among authors: pyle ad. Mol Ther Nucleic Acids. 2020 Aug 29;22:500-509. doi: 10.1016/j.omtn.2020.08.031. eCollection 2020 Dec 4. Mol Ther Nucleic Acids. 2020. PMID: 33230452 Free PMC article.

10

Generation of PAX7 Reporter Cells to Investigate Skeletal Myogenesis from Human Pluripotent Stem Cells.

Xi H, Young CS, Pyle AD. Xi H, et al. Among authors: pyle ad. STAR Protoc. 2020 Nov 5;1(3):100158. doi: 10.1016/j.xpro.2020.100158. eCollection 2020 Dec 18. STAR Protoc. 2020. PMID: 33377052 Free PMC article.

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