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IL-12 sensing in neurons induces neuroprotective CNS tissue adaptation and attenuates neuroinflammation in mice.
Andreadou M, Ingelfinger F, De Feo D, Cramer TLM, Tuzlak S, Friebel E, Schreiner B, Eede P, Schneeberger S, Geesdorf M, Ridder F, Welsh CA, Power L, Kirschenbaum D, Tyagarajan SK, Greter M, Heppner FL, Mundt S, Becher B. Andreadou M, et al. Among authors: heppner fl. Nat Neurosci. 2023 Oct;26(10):1701-1712. doi: 10.1038/s41593-023-01435-z. Epub 2023 Sep 25. Nat Neurosci. 2023. PMID: 37749256 Free PMC article.
Modeling multiple sclerosis in laboratory animals.
Schreiner B, Heppner FL, Becher B. Schreiner B, et al. Among authors: heppner fl. Semin Immunopathol. 2009 Nov;31(4):479-95. doi: 10.1007/s00281-009-0181-4. Epub 2009 Oct 3. Semin Immunopathol. 2009. PMID: 19802608 Review.
Primary oligodendrocyte death does not elicit anti-CNS immunity.
Locatelli G, Wörtge S, Buch T, Ingold B, Frommer F, Sobottka B, Krüger M, Karram K, Bühlmann C, Bechmann I, Heppner FL, Waisman A, Becher B. Locatelli G, et al. Among authors: heppner fl. Nat Neurosci. 2012 Feb 26;15(4):543-50. doi: 10.1038/nn.3062. Nat Neurosci. 2012. PMID: 22366759
An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration.
Lehmann SM, Krüger C, Park B, Derkow K, Rosenberger K, Baumgart J, Trimbuch T, Eom G, Hinz M, Kaul D, Habbel P, Kälin R, Franzoni E, Rybak A, Nguyen D, Veh R, Ninnemann O, Peters O, Nitsch R, Heppner FL, Golenbock D, Schott E, Ploegh HL, Wulczyn FG, Lehnardt S. Lehmann SM, et al. Among authors: heppner fl. Nat Neurosci. 2012 Jun;15(6):827-35. doi: 10.1038/nn.3113. Nat Neurosci. 2012. PMID: 22610069
211 results